The natural history of symptomatic COVID-19 during the first wave in Catalonia.
The natural history of symptomatic COVID-19 during the first wave in Catalonia.
复制标题
在加泰罗尼亚第一波中，有症状的covid-19的自然历史。
DOI：
10.1038/s41467-021-21100-y
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发表时间：
2021-02-03
影响因子：
16.6
通讯作者：
Duarte-Salles T
中科院分区：
文献类型：
--
作者：
Burn E;Tebé C;Fernandez-Bertolin S;Aragon M;Recalde M;Roel E;Prats-Uribe A;Prieto-Alhambra D;Duarte-Salles T
2019冠状病毒病（COVID-19）的自然史尚未完全描述。在这里，我们使用来自初级保健研究信息系统（SIDIAP）的患者水平数据来总结西班牙加泰罗尼亚的COVID-19结果。我们纳入了来自普通人群的5，586，521人。其中，102，002人在门诊诊断为COVID-19，16，901人因COVID-19住院，5273人于二零二零年三月一日至五月六日期间因COVID-19确诊或住院后死亡。年龄较大、男性和合并症通常都与不良结局相关。这些研究结果表明，仍然需要保护那些高风险的不良结果，特别是老年人，免受COVID-19的影响，并为那些出现症状的疾病提供适当的护理。虽然年轻人群的住院和死亡风险较低，但有必要限制他们在社区传播中的作用。建立COVID-19的自然史需要基于人群的队列纵向数据。在这里，作者使用相关的初级保健，测试和医院数据来描述西班牙加泰罗尼亚约550万人口中约10万名COVID-19诊断者的疾病。
The natural history of coronavirus disease 2019 (COVID-19) has yet to be fully described. Here, we use patient-level data from the Information System for Research in Primary Care (SIDIAP) to summarise COVID-19 outcomes in Catalonia, Spain. We included 5,586,521 individuals from the general population. Of these, 102,002 had an outpatient diagnosis of COVID-19, 16,901 were hospitalised with COVID-19, and 5273 died after either being diagnosed or hospitalised with COVID-19 between 1st March and 6th May 2020. Older age, being male, and having comorbidities were all generally associated with worse outcomes. These findings demonstrate the continued need to protect those at high risk of poor outcomes, particularly older people, from COVID-19 and provide appropriate care for those who develop symptomatic disease. While risks of hospitalisation and death were lower for younger populations, there is a need to limit their role in community transmission. Establishing the natural history of COVID-19 requires longitudinal data from population-based cohorts. Here, the authors use linked primary care, testing, and hospital data to describe the disease in ~100,000 individuals with a COVID-19 diagnosis among a population of ~5.5 million in Catalonia, Spain.
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影响因子：
2
作者：
Putter, H.;Fiocco, M.;Geskus, R. B.
通讯作者：
Geskus, R. B.
影响因子：
16.6
作者：
Burn E;You SC;Sena AG;Kostka K;Abedtash H;Abrahão MTF;Alberga A;Alghoul H;Alser O;Alshammari TM;Aragon M;Areia C;Banda JM;Cho J;Culhane AC;Davydov A;DeFalco FJ;Duarte-Salles T;DuVall S;Falconer T;Fernandez-Bertolin S;Gao W;Golozar A;Hardin J;Hripcsak G;Huser V;Jeon H;Jing Y;Jung CY;Kaas-Hansen BS;Kaduk D;Kent S;Kim Y;Kolovos S;Lane JCE;Lee H;Lynch KE;Makadia R;Matheny ME;Mehta PP;Morales DR;Natarajan K;Nyberg F;Ostropolets A;Park RW;Park J;Posada JD;Prats-Uribe A;Rao G;Reich C;Rho Y;Rijnbeek P;Schilling LM;Schuemie M;Shah NH;Shoaibi A;Song S;Spotnitz M;Suchard MA;Swerdel JN;Vizcaya D;Volpe S;Wen H;Williams AE;Yimer BB;Zhang L;Zhuk O;Prieto-Alhambra D;Ryan P
通讯作者：
Ryan P
影响因子：
168.9
作者：
Pollan, Marina;Perez-Gomez, Beatriz;Yotti, Raquel
通讯作者：
Yotti, Raquel
影响因子：
16.6
作者：
Griffith GJ;Morris TT;Tudball MJ;Herbert A;Mancano G;Pike L;Sharp GC;Sterne J;Palmer TM;Davey Smith G;Tilling K;Zuccolo L;Davies NM;Hemani G
通讯作者：
Hemani G
影响因子：
105.7
作者：
Docherty, Annemarie B.;Harrison, Ewen M.;Semple, Malcolm G.
通讯作者：
Semple, Malcolm G.