Estimation of multi-mycotoxin contamination in South African compound feeds.

Estimation of multi-mycotoxin contamination in South African compound feeds.
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DOI:
10.3390/toxins4100836
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发表时间:
2012-10
期刊:
影响因子:
4.2
通讯作者:
Haggblom P
Haggblom P
中科院分区:
医学2区
文献类型:
--
作者:
Njobeh PB;Dutton MF;Åberg AT;Haggblom P

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对来自南非的92种商业配合饲料进行了各种真菌毒素的调查。数据显示,饲料污染发生率最高的是伏马菌素(FB)(范围:104-2999µg/kg),其次是脱氧镰刀菌烯醇(DON)(范围:124-2352µg/kg)和玉米赤霉烯酮(ZEA)(范围:30-610µg/kg)。赭曲霉毒素A (OTA)和黄曲霉毒素(AF)污染样品的发生率普遍较低,即4%和30%的样品含量在6.4 - 17.1µg/kg(平均9.9µg/kg)之间,AF含量在0.2 - 71.8µg/kg(平均9.0µg/kg)之间。没有样品含有T-2毒素或HT-2毒素。然而,所有分析的样品都被至少一种霉菌毒素污染,其中大多数含有几种霉菌毒素。特别是,4个阳性样品中有3个主要是牛饲料,它们的OTA含量相对较高(范围从7到17.1µg/kg),同时也含有大量的AF (bb0 ~ 27.5µg/kg)以及FB、DON和ZEA。除少数样品外,真菌毒素的水平可被认为对南非的牲畜生产是安全的。然而,真菌毒素在样品中持续共存,特别是那些高浓度的真菌毒素,即AF和OTA,与所研究的其他真菌毒素一起,可能会在动物中引起协同或加性效应。这应引起关注,因为多重污染可能对牲畜生产和健康构成风险。
A total of 92 commercial compound feeds from South Africa were investigated for various mycotoxins. The data reveal the highest incidence of feed contamination for fumonisins (FB) (range: 104–2999 µg/kg) followed by deoxynivalenol (DON) (range: 124–2352 µg/kg) and zearalenone (ZEA) (range: 30–610 µg/kg). The incidence of ochratoxin A (OTA) and aflatoxins (AF)-contaminated samples were generally low, i.e., 4% and 30% of samples with levels ranging between 6.4 and 17.1 µg/kg (mean: 9.9 µg/kg) for OTA and 0.2 to 71.8 µg/kg (mean: 9.0 µg/kg) for AF. No samples contained T-2 toxin or HT-2 toxin. However, all samples analyzed were contaminated with at least one mycotoxin with a majority containing several mycotoxins. In particular, 3 of 4 positive samples mainly cattle feeds that had relatively high contents of OTA (ranging from 7 to 17.1 µg/kg) also contained high amounts of AF (>27.5 µg/kg) together with FB, DON and ZEA. Apart from a few samples, the levels of mycotoxins may be regarded as safe for livestock production in South Africa. However, the persistent co-occurrence of mycotoxins in samples, especially those at high concentrations, i.e., AF and OTA, together with other mycotoxins studied, may elicit synergistic or additive effects in animals. This should raise concern as multiple contaminations may pose a risk to livestock production and health.
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