Experimental verification of a Monte Carlo-based MLC simulation model for IMRT dose calculation.
Experimental verification of a Monte Carlo-based MLC simulation model for IMRT dose calculation.
复制标题
用于 IMRT 剂量计算的基于蒙特卡罗的 MLC 模拟模型的实验验证。
DOI：
10.1118/1.2428405
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发表时间：
2007
期刊：
影响因子：
3.8
通讯作者：
Chetty,IndrinJ
中科院分区：
文献类型：
--
作者：
Tyagi,Neelam;Moran,JeanM;Litzenberg,DaleW;Bielajew,AlexF;Fraass,BenedickA;Chetty,IndrinJ
叶间和叶内传输以及头部散射在基于调强放射治疗 (IMRT) 的治疗实施中发挥着重要作用。因此，为了准确计算 IMRT 计划过程中的剂量，除了加速器治疗头中的其他组件之外，还必须对多叶准直器 (MLC) 的详细几何形状进行准确建模。在本文中，我们使用蒙特卡罗方法 (MC) 开发了瓦里安 120 叶 MLC 的综合模型，并将其与不同 IMRT 传输环境下均匀体模几何形状的测量结果进行了比较。我们在 DPM MC 代码中开发了一个几何模块来模拟详细的 MLC 设计和准直钳口。进行了包括泄漏、叶片定位和静态 MLC 形状在内的测试，以验证 MLC 模型内传输的准确性。计算显示，对于这些静态形状，薄膜和离子室测量在高剂量区域的一致性在 2% 以内。还计算了乳腺 [节段 MLC (SMLC) 和动态 MLC (DMLC)]、前列腺 (SMLC) 和头颈分割野 (SMLC) 的临床 IMRT 治疗计划，并与胶片测量进行比较。选择这样一系列的情况来研究模型的准确性，作为小束图案、小束宽度和场尺寸的调制的函数。除头颈分割场外，所有 IMRT 光束的胶片数据均一致，在高剂量区域显示差异高达 5%。讨论了这些比较中不确定性的各种来源。
Inter‐ and intra‐leaf transmission and head scatter can play significant roles in intensity modulated radiation therapy (IMRT)‐based treatment deliveries. In order to accurately calculate the dose in the IMRT planning process, it is therefore important that the detailed geometry of the multi‐leaf collimator (MLC), in addition to other components in the accelerator treatment head, be accurately modeled. In this paper, we have used the Monte Carlo method (MC) to develop a comprehensive model of the Varian 120 leaf MLC and have compared it against measurements in homogeneous phantom geometries under different IMRT delivery circumstances. We have developed a geometry module within the DPM MC code to simulate the detailed MLC design and the collimating jaws. Tests consisting of leakage, leaf positioning and static MLC shapes were performed to verify the accuracy of transport within the MLC model. The calculations show agreement within 2% in the high dose region for both film and ion‐chamber measurements for these static shapes. Clinical IMRT treatment plans for the breast [both segmental MLC (SMLC) and dynamic MLC (DMLC)], prostate (SMLC) and head and neck split fields (SMLC) were also calculated and compared with film measurements. Such a range of cases were chosen to investigate the accuracy of the model as a function of modulation in the beamlet pattern, beamlet width, and field size. The overall agreement is within of the film data for all IMRT beams except the head and neck split field, which showed differences up to 5% in the high dose regions. Various sources of uncertainties in these comparisons are discussed.
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影响因子：
2.1
作者：
Miften M;Wiesmeyer M;Kapur A;Ma CM
通讯作者：
Ma CM
DOI：
10.1016/s0958-3947(01)00061-9
发表时间：
2001-01-01
期刊：
Medical dosimetry : official journal of the American Association of Medical Dosimetrists
影响因子：
--
作者：
Pawlicki, T;Ma, C M
通讯作者：
Ma, C M
影响因子：
3.8
作者：
Mohan, R;Arnfield, M;Siebers, J
通讯作者：
Siebers, J
urocor prostaseed 125I 源剂量测定参数的蒙特卡罗计算。
DOI：
--
发表时间：
2002
期刊：
Medical Physics (Lancaster)
影响因子：
--
作者：
Zuofeng Li
通讯作者：
Zuofeng Li
均匀介质和界面处的蒙特卡罗剂量计算：GEPTS、EGSnrc、MCNP 和测量之间的比较。
影响因子：
3.8
作者：
Chibani,Omar;Li,XAllen
通讯作者：
Li,XAllen