Evaluation of the Patient Health Questionnaire-9 Item for detecting major depression among adolescents.
Evaluation of the Patient Health Questionnaire-9 Item for detecting major depression among adolescents.
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DOI：
10.1542/peds.2010-0852
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发表时间：
2010-12
期刊：
影响因子：
8
通讯作者：
Katon W
中科院分区：
文献类型：
--
作者：
Richardson LP;McCauley E;Grossman DC;McCarty CA;Richards J;Russo JE;Rockhill C;Katon W
本研究的目的是检验《患者健康问卷-9》(PHQ-9)作为青少年抑郁筛查工具的表现特点和效度。PHQ-9是由442名年轻人(13-17岁)完成的，他们参加了一个大型医疗保健服务系统，并参与了一项关于抑郁症结果的研究。根据独立的结构化心理健康访谈(儿童诊断访谈计划，DISC-IV)评估标准的效度和表现特征。结构效度是通过检查PHQ-9和自我报告的功能损害测量之间的关系，以及父母对儿童心理社会损害和内化症状的报告来检验的。对于符合≥-IV诊断标准的青少年，PHQ-9评分DSM-11的灵敏度为89.5%，特异度为77.5%。在ROC分析中，PHQ-9的曲线下面积为0.88(95%CI=0.82至0.94)，切割点11是在不损失特异性的情况下最大限度地提高敏感性的最佳切入点。PHQ-9得分的增加与功能损害程度的增加以及父母报告的内化症状和心理社会问题显著相关。尽管最佳临界点在青少年中较高，但PHQ-9的敏感度和特异度与成人相似。该工具的简洁性和易分性使该工具成为寻求在初级保健环境中实施抑郁症筛查的提供者和研究人员的极佳选择。
The purpose of this study was to examine the performance characteristics and validity of the Patient Health Questionnaire - 9 item (PHQ-9) as a screening tool for depression among adolescents. The PHQ-9 was completed by 442 youth (13-17 years) who were enrolled in a large healthcare delivery system and participating in a study on depression outcomes. Criterion validity and performance characteristics were assessed against an independent structured mental health interview (the Child Diagnostic Interview Schedule, DISC-IV). Construct validity was tested by examining associations between the PHQ-9 and a self-report measure of functional impairment, as well as parental reports of child psychosocial impairment and internalizing symptoms. A PHQ-9 score ≥11 had a sensitivity of 89.5% and specificity of 77.5% for detecting youth meeting DSM-IV criteria for major depression on the DISC-IV. On ROC analysis the PHQ-9 had an area under the curve of 0.88 (95% CI = 0.82 to 0.94) and the cut point of 11 was optimal for maximizing sensitivity without loss of specificity. Increasing PHQ-9 scores were significantly correlated with increasing levels of functional impairment, as well as parental report of internalizing symptoms and psychosocial problems. Although the optimal cut point is higher among adolescents, the sensitivity and specificity of the PHQ-9 are similar to those of adult populations. The brief nature and ease of scoring of this instrument make this tool an excellent choice for providers and researchers seeking to implement depression screening in primary care settings.
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DOI：
10.1097/00004583-200001000-00014
发表时间：
2000-01-01
影响因子：
13.3
作者：
Shaffer, D;Fisher, P;Schwab-Stone, ME
通讯作者：
Schwab-Stone, ME
DOI：
10.1016/j.ambp.2008.01.003
发表时间：
2008-05-01
期刊：
AMBULATORY PEDIATRICS
影响因子：
--
作者：
Katon, Wayne;Russo, Joan;Lozano, Paula
通讯作者：
Lozano, Paula
影响因子：
7.6
作者：
Winter, LB;Steer, RA;Beck, AT
通讯作者：
Beck, AT
影响因子：
4.4
作者：
Yates, P;Kramer, T;Garralda, E
通讯作者：
Garralda, E
影响因子：
8
作者：
Zuckerbrot, Rachel A.;Maxon, Laura;Shaffer, David
通讯作者：
Shaffer, David