Regulation of blood flow at the onset of exercise by feed forward and feedback mechanisms.
Regulation of blood flow at the onset of exercise by feed forward and feedback mechanisms.
复制标题
通过前馈和反馈机制在运动开始时调节血流。
DOI：
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
R. Hughson
中科院分区：
文献类型：
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作者：
R. Hughson
运动开始后，血流迅速适应，以满足骨骼肌的代谢需求。这篇综述探讨了血流如何快速适应的问题，以及适应的机制主要是从控制理论的角度。最近的几篇论文表明，O2运输的速度，预计在很宽的范围内的工作率的代谢需求。当从控制理论的角度考虑时，这意味着涉及前馈控制。虽然在肌肉泵中存在一种非常重要的前馈机制，其随着运动的开始而被激活，但其他证据表明，调节血流以匹配代谢需求依赖于来自与代谢需求成比例释放的局部扩张因子的反馈控制。这些具有不同起始时间的不同机制意味着血液流动适应至少两个不同阶段的运动需求。适应的时间过程在工作速率之间变化很大，表明血流控制不能由线性控制系统描述，并且负责血管舒张的机制取决于工作速率。
Blood flow adapts quickly after the onset of exercise to meet the metabolic demands of skeletal muscle. This review approaches the issue of how rapidly blood flow adapts and what the mechanisms for adaptation are primarily from a control theory perspective. Several recent papers have suggested that O2 transport proceeds at a rate that anticipates the metabolic demand over a very wide range of work rates. When considered from a control theory perspective, this implies involvement of feed forward control. Although there is one very important feed forward mechanism in the muscle pump that is activated with the onset of exercise, other evidence suggests that adjustment of blood flow to match the metabolic demand relies on feedback control from local dilator factors released in proportion to the metabolic demand. These distinct mechanisms with different onset times mean that blood flow adapts to the exercise demand with at least two distinct phases. The time course of the adaptation varies greatly between work rates, showing that blood flow control cannot be described by a linear control system and that the mechanisms responsible for vasodilation are dependent on work rate.
乙酰胆碱和一氧化氮对运动开始和恢复时前臂血流的贡献。
DOI：
10.1152/ajpheart.1997.273.5.h2388
发表时间：
1997
期刊：
The American journal of physiology
影响因子：
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作者：
Shoemaker,JK;Halliwill,JR;Hughson,RL;Joyner,MJ
通讯作者：
Joyner,MJ
骨骼肌阻力脉管系统血流控制的协调。
DOI：
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发表时间：
1995
期刊：
Medicine and science in sports and exercise.
影响因子：
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作者：
Segal,SS;Kurjiaka,DT
通讯作者：
Kurjiaka,DT