T4-related bacteriophage LIMEstone isolates for the control of soft rot on potato caused by 'Dickeya solani'.
T4-related bacteriophage LIMEstone isolates for the control of soft rot on potato caused by 'Dickeya solani'.
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T4相关的噬菌体石灰石分离株,用于控制由“ Dickeya Solani”引起的马铃薯的软腐烂。
DOI:
10.1371/journal.pone.0033227
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发表时间:
2012
期刊:
影响因子:
3.7
通讯作者:
Lavigne R
中科院分区:
文献类型:
--
作者:
Adriaenssens EM;Van Vaerenbergh J;Vandenheuvel D;Dunon V;Ceyssens PJ;De Proft M;Kropinski AM;Noben JP;Maes M;Lavigne R
The bacterium ‘Dickeya solani’, an aggressive biovar 3 variant of Dickeya dianthicola, causes rotting and blackleg in potato. To control this pathogen using bacteriophage therapy, we isolated and characterized two closely related and specific bacteriophages, vB_DsoM_LIMEstone1 and vB_DsoM_LIMEstone2. The LIMEstone phages have a T4-related genome organization and share DNA similarity with Salmonella phage ViI. Microbiological and molecular characterization of the phages deemed them suitable and promising for use in phage therapy. The phages reduced disease incidence and severity on potato tubers in laboratory assays. In addition, in a field trial of potato tubers, when infected with ‘Dickeya solani’, the experimental phage treatment resulted in a higher yield. These results form the basis for the development of a bacteriophage-based biocontrol of potato plants and tubers as an alternative for the use of antibiotics.
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影响因子:
3.7
作者:
Denou, Emmanuel;Bruttin, Anne;Zuber, Sophie
通讯作者:
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影响因子:
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影响因子:
3.2
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通讯作者:
Perna, Nicole T.