In vivo measurement of the subchondral bone thickness of lumbar facet joint using magnetic resonance imaging.
In vivo measurement of the subchondral bone thickness of lumbar facet joint using magnetic resonance imaging.
复制标题
使用磁共振成像在体内测量腰部面关节的软骨下骨厚度。
DOI：
10.1016/j.joca.2010.10.015
复制
发表时间：
2011-01
影响因子：
7
通讯作者：
Inoue, N.
中科院分区：
文献类型：
--
作者：
Duan, C. Y.;Orias, A. A. Espinoza;Shott, S.;An, H. S.;Andersson, G. B. J.;Hu, J. Z.;Lu, H. B.;Inoue, N.
测量不同性别、年龄组、有或无腰痛症状组和脊柱节段的小关节软骨下骨的体内厚度。对81例受试者（41例男性和40例女性，平均年龄37.6岁）进行了腰椎（L1-L2至L5-S1）磁共振（MR）成像。使用带有定制的图像处理算法的MR图像以及使用每个小关节的中间轴向切片的多阈值分割技术，在1，620个小关节中测量软骨下骨的厚度。该方法与12具尸体小关节，扫描与MR和微型计算机断层扫描图像进行了验证。1，620个分析关节的总体平均厚度值为1.56 ± 0.01 mm。在无腰痛的受试者中，软骨下骨厚度值显示出随脊柱节段的连续降低而显著增加。无症状女性的小关节软骨下骨厚度远小于无症状男性。在女性和男性无症状受试者中，上级关节面的平均软骨下骨厚度大于下级关节面。这项研究是第一次使用经验证的基于MR的技术定量显示软骨下骨厚度。无症状男性的软骨下骨厚度更大，并随着脊柱节段的降低而增加。这些结果可能表明，软骨下骨厚度增加负荷。此外，在所有病例中，无论性别、年龄或脊柱节段，无腰痛的受试者的上级关节突软骨下骨均厚于下关节突。需要更多的研究来将软骨下骨的微观结构与小关节运动学和脊柱负荷联系起来。
To measure in vivo thicknesses of the facet joint subchondral bone across genders, age groups, with or without low back pain symptom groups and spinal levels. Lumbar (L1–L2 to L5-S1) magnetic resonance (MR) imaging was performed in 81 subjects (41 males and 40 females, mean age 37.6 years). Thicknesses of the subchondral bone were measured in 1,620 facet joints using the MR images with custom-written image processing algorithms together with a multi-threshold segmentation technique using each facet joint’s middle axial-slice. This method was validated with 12 cadaver facet joints, scanned with both MR and micro-computed tomography images. An overall average thickness value for the 1,620 analyzed joints was measured as 1.56 ± 0.01 mm. The subchondral bone thickness values showed significant increases with successive lower spinal levels in the subjects without low back pain. The facet joint subchondral bone thickness in asymptomatic females was much smaller than in asymptomatic males. Mean subchondral bone thickness in the superior facet was greater than that in the inferior facet in both female and male asymptomatic subjects. This study is the first to quantitatively show subchondral bone thickness using a validated MR-based technique. The subchondral bone thickness was greater in asymptomatic males and increased with each successive lower spinal level. These findings may suggest that the subchondral bone thickness increases with loading. Furthermore, the superior facet subchondral bone was thicker than the inferior facet in all cases regardless of gender, age or spinal level in the subjects without low back pain. More research is needed to link subchondral bone microstructure to facet joint kinematics and spinal loads.
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DOI：
10.2106/00004623-199072030-00013
发表时间：
1990-03-01
影响因子：
5.3
作者：
BODEN, SD;DAVIS, DO;WIESEL, SW
通讯作者：
WIESEL, SW
DOI：
10.1302/0301-620x.66b5.6501365
发表时间：
1984-01-01
影响因子：
--
作者：
DUNLOP, RB;ADAMS, MA;HUTTON, WC
通讯作者：
HUTTON, WC
影响因子：
3
作者：
YANG, KH;KING, AI
通讯作者：
KING, AI
影响因子：
2.4
作者：
Eckstein, F;Milz, S;Putz, R
通讯作者：
Putz, R
影响因子：
--
作者：
SIMKIN, PA;GRANEY, DO;FIECHTNER, JJ
通讯作者：
FIECHTNER, JJ