Pain at multiple body sites and health-related quality of life in older adults: results from the North Staffordshire Osteoarthritis Project.
Pain at multiple body sites and health-related quality of life in older adults: results from the North Staffordshire Osteoarthritis Project.
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DOI：
10.1093/rheumatology/keu240
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发表时间：
2014-11
期刊：
影响因子：
--
通讯作者：
McBeth J
中科院分区：
文献类型：
--
作者：
Lacey RJ;Belcher J;Rathod T;Wilkie R;Thomas E;McBeth J
目标.疼痛部位的数量（Pain site，HSI）是健康相关生活质量（HRQoL）的一个潜在的重要指标，但在老年人中尚未探索。这项横断面研究调查了老年人（包括最年长的老年人）中的抑郁症是否与较差的精神和身体HRQoL独立相关，以及这种相关性是否受年龄的影响。方法.向英国北斯塔福德郡年龄≥50岁的成人人群样本发送了一份邮寄问卷，包括12项简明健康调查表（SF-12）精神健康量表（MCS）和身体健康量表（PCS）、一个空白身体疼痛模型、社会人口统计学、健康行为和发病率问题。受试者在人体模型上对过去4周内持续≥1天的疼痛部位涂上阴影。OA咨询数据获得的参与者同意医疗记录审查。结果共有13986人（调整后的反应70.6%）完成了问卷调查，其中12408提供了完整的疼痛数据。报告的中位数为4 [四分位距（IQR）0-8]。一般线性模型显示，增加的BMI与较差的MCS（β = −0.43，95%CI −0.46，−0.40）和PCS（β = −0.87，95%CI −0.90，−0.84）显著相关。协变量调整减弱了相关性，但仍具有显著性（MCS：β = −0.28，95%CI −0.31，−0.24; PCS：β = −0.63，95%CI −0.66，−0.59）。之间的关联性和MCS或PCS是缓和的年龄，但最强的协会不是在最古老的老。结论在老年人中，HRQoL似乎是一个潜在的可修改的目标，以改善身体和精神HRQoL。未来的分析应调查随着时间的推移，在老年人的HRQoL的影响。
Objectives. Number of pain sites (NPS) is a potentially important marker of health-related quality of life (HRQoL) but remains unexplored in older people. This cross-sectional study investigated whether, in older people including the oldest old, NPS was independently associated with poorer mental and physical HRQoL and if the association was moderated by age. Methods. A postal questionnaire sent to a population sample of adults aged ≥50 years in North Staffordshire, UK, included the 12-item Short Form Health Survey (SF-12) mental component summary (MCS) and physical component summary (PCS), a blank body pain manikin, socio-demographic, health behaviour and morbidity questions. Participants shaded sites of pain lasting ≥1 day in the past 4 weeks on the manikin. OA consultation data were obtained for participants consenting to medical records review. Results. A total of 13 986 individuals (adjusted response 70.6%) completed a questionnaire, of which 12 408 provided complete pain data. The median NPS reported was 4 [interquartile range (IQR) 0–8]. General linear models showed that an increasing NPS was significantly associated with poorer MCS (β = −0.43, 95% CI −0.46, −0.40) and PCS (β = −0.87, 95% CI −0.90, −0.84). Adjustment for covariates attenuated the associations but they remained significant (MCS: β = −0.28, 95% CI −0.31, −0.24; PCS: β = −0.63, 95% CI −0.66, −0.59). The association between NPS and MCS or PCS was moderated by age, but the strongest associations were not in the oldest old. Conclusion. NPS appears to be a potentially modifiable target for improving physical and mental HRQoL in older people. Future analyses should investigate the influence of NPS on HRQoL over time in older people.
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7.4
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Lee, D. M.;Pendleton, N.;McBeth, J.
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