Cardiac Magnetic Resonance Assessment of the Protective Effect of Remote Ischemic Postconditioning on Coronary Microcirculation after Reperfusion Therapy for Acute ST-Segment Elevation Myocardial Infarction.
Cardiac Magnetic Resonance Assessment of the Protective Effect of Remote Ischemic Postconditioning on Coronary Microcirculation after Reperfusion Therapy for Acute ST-Segment Elevation Myocardial Infarction.
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DOI：
10.1155/2022/5629763
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发表时间：
2022
影响因子：
--
通讯作者：
Li, Yajuan
中科院分区：
文献类型：
--
作者：
Wu, Chun;Duan, Zhiyong;Shu, Jin;Li, Yajuan
本研究旨在评价心肌梗死再灌注患者冠状动脉微循环功能的特点及其对心肌梗死后心功能、心肌活动、室壁运动恢复和远端心肌重构的预测价值。材料和方法。本次回顾性研究选取2017年8月至2021年8月在我院治疗的293例心肌梗死患者作为研究对象，其中13例因转院、搬家而脱落，其余按急诊经皮冠状动脉介入治疗（PCI）和择期PCI分为急诊组和择期组各140例。比较两组患者的心肌梗死体积、心室容积、微循环阻塞体积、心室容积、微循环阻塞体积/心肌梗死体积、LVEF，并结合血压、肌钙蛋白T进行CMR对比分析、血流动力学、心功能指标差异。结果血流动力学两组患者术后不同时间的CO、CI、SV、SI、LVSW 1和LCW差异有统计学意义，急诊组患者术后7-10 d的EDV和ESV明显低于择期组; 3个月后两组EDV、ESV、LVEF均有所改善，而EDV、ESV、急诊组LVEF改善明显优于择期组，差异有统计学意义（P <0. 05）。急诊组PCI术后7 ~ 10 d心肌梗死质量、VSM评分和室壁运动异常评分明显低于择期组，PCI术后3个月两组心肌梗死质量、VSM评分和室壁运动异常评分均改善;急诊组心肌梗死质量和VSM评分改善程度明显优于择期组（P < 0.05）。结论急性心肌梗死患者急诊PCI治疗效果显著，可对其心肌梗死后左室功能进行评价，并在冠心病的治疗中，对心肌梗死的诊断有一定的参考价值。
This study intends to evaluate the characteristics of coronary microcirculatory function in patients with myocardial infarction undergoing reperfusion and its predictive value in assessing cardiac function, myocardial activity, recovery of ventricular wall motion after infarction, and distant myocardial remodeling by cardiac magnetic resonance technique (CMRI). Materials and Methods. The 293 cases of patients with myocardial infarction treated in our hospital from August 2017 to August 2021 were selected as the subjects of this retrospective study, 13 cases were shed due to transfer and moving, and the rest were divided into 140 cases each in the emergency and elective groups according to emergency percutaneous coronary intervention (PCI) and elective PCI. The patients' myocardial infarct volume ventricular volume, microcirculatory obstruction volume ventricular volume, microcirculatory obstruction volume/myocardial infarct volume, and LVEF, combined with BP and troponin T, were analysed by CMR for comparative analysis, hemodynamic, and cardiac function index differences. Results. The hemodynamics (CO, CI, SV, SI, LVSW1, and LCW) measured at different times were significantly different between the two groups; patients in the emergency group had significantly lower EDV and ESV than the elective group at 7-10 d postoperatively; and EDV, ESV, and LVEF improved in both groups after 3 months, while EDV, ESV, and LVEF improved significantly better in the emergency group than in the elective group, and the difference was statistically significant (P < 0.05). The myocardial infarct quality, VSM score, and ventricular wall motion abnormality score were significantly lower in the emergency group than in the elective group from 7 to 10 d after PCI; myocardial infarct quality, VSM score, and ventricular wall motion abnormality score improved in both groups at 3 months after PCI; and the degree of improvement of myocardial infarct quality and VSM score was significantly better in the emergency group than in the elective group (P < 0.05). Conclusion. Acute myocardial infarction patients with significant effect of emergency PCI treatment can be on their postmyocardial infarction left ventricular function, and in the treatment of coronary heart disease, myocardial infarction diagnosis has a certain reference value.
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影响因子：
1.9
作者：
Mitsis A;Gragnano F
通讯作者：
Gragnano F
DOI：
10.3760/cma.j.issn.0253-3758.2016.05.006
发表时间：
2016-05-24
期刊：
Zhonghua xin xue guan bing za zhi
影响因子：
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作者：
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影响因子：
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作者：
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Agoston-Coldea, Lucia
影响因子：
3.7
作者：
Arora, Garima;Bittner, Vera
通讯作者：
Bittner, Vera
DOI：
10.3889/oamjms.2018.270
发表时间：
2018-12-20
影响因子：
--
作者：
Habeeb, Nevin Mohamed;Youssef, Omneya Ibrahim;Hussein, Walaa Hamed
通讯作者：
Hussein, Walaa Hamed