Heterogeneity of basal keratinocytes: nonrandom distribution of thymidine-labeled basal cells in confluent cultures is not a technical artifact.

Heterogeneity of basal keratinocytes: nonrandom distribution of thymidine-labeled basal cells in confluent cultures is not a technical artifact.
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基底角质形成细胞的异质性:汇合培养物中胸苷标记基底细胞的非随机分布不是技术产物。

DOI:
10.1111/1523-1747.ep12273479
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发表时间:
1985
期刊:
The Journal of investigative dermatology
影响因子:
--
通讯作者:
Jane F. Lavigne
Jane F. Lavigne
中科院分区:
--
文献类型:
--
作者:
L. Milstone;Jane F. Lavigne

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[3H] dthd标记的融合角化细胞培养物的基底表面放射自显影显示增殖细胞具有非随机的模式分布。同样,未标记的细胞也非随机地出现在集群中。我们在此表明,在培养的一些基底细胞中检测到DNA合成的失败不是由于标记细胞核与放射照相乳剂的物理分离或扩散屏障阻止[3H]dThd到达基底细胞而引起的人工产物。
Basal surface autoradiography of [3H]dThd-labeled, confluent, keratinocyte cultures reveals that proliferating cells have a nonrandom, patterned distribution. Unlabeled cells, likewise, appear nonrandomly in clusters. We show here that failure to detect DNA synthesis in some basal cells in culture is not an artifact caused either by physical separation of the labeled nuclei from the radiographic emulsion or by a diffusion barrier that would prevent [3H]dThd from reaching basal cells.
DOI: 10.1126/science.7058342
发表时间: 1982-01-01
期刊: SCIENCE
影响因子: 56.9
作者:
LAVKER, RM;SUN, TT
通讯作者: SUN, TT
DOI: 10.1126/science.6791284
发表时间: 1981-01-01
期刊: SCIENCE
影响因子: 56.9
作者:
SLAGA, TJ;KLEINSZANTO, AJP;TROSKO, JE
通讯作者: TROSKO, JE
视黄酸导致复层鳞状上皮汇合培养物中的细胞过早脱落。
DOI: 10.1111/1523-1747.ep12500073
发表时间: 1982
期刊: The Journal of investigative dermatology
影响因子: --
作者:
Milstone,LM;McGuire,J;LaVigne,JF
通讯作者: LaVigne,JF