Frailty assessment as part of transplant listing: yes, no or maybe?
Frailty assessment as part of transplant listing: yes, no or maybe?
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DOI：
10.1093/ckj/sfac277
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发表时间：
2023-05
影响因子：
4.6
通讯作者：
中科院分区：
文献类型：
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Frailty, characterized by a decreased physiological reserve and an increased vulnerability to stressors, is common among kidney transplant (KT) candidates and recipients. In this review, we present and summarize the key arguments for and against the assessment of frailty as part of KT evaluation. The key arguments for including frailty were: (i) sheer prevalence and far-reaching consequences of frailty on KT, and (ii) the ability to conduct a more holistic and objective evaluation of candidates, removing the inaccuracy associated with ‘eye-ball’ assessments of transplant fitness. The key argument against were: (i) lack of agreement on the definition of frailty and which tools should be used in renal populations, (ii) a lack of clarity on how, by whom and how often frailty assessments should be performed, and (iii) a poor understanding of how acute stressors affect frailty. However, it is the overwhelming opinion that the time has come for frailty assessments to be incorporated into KT listing. Although ongoing areas of uncertainty exist and further evidence development is needed, the well-established impact of frailty on clinical and experiential outcomes, the invaluable information obtained from frailty assessments, and the potential for intervention outweigh these limitations. Proactive and early identification of frailty allows for individualized and improved risk assessment, communication and optimization of candidates.
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影响因子：
3.8
作者：
Chen X;Kong H;Luo L;Han S;Lei T;Yu H;Guo N;Li C;Peng S;Dong X;Yang H;Wu M
通讯作者：
Wu M
影响因子：
4.2
作者：
Chu, Nadia M.;Chen, Xiaomeng;McAdams-DeMarco, Mara A.
通讯作者：
McAdams-DeMarco, Mara A.
影响因子：
--
作者：
Garonzik-Wang, Jacqueline M.;Govindan, Priyanka;Segev, Dorry L.
通讯作者：
Segev, Dorry L.
影响因子：
6.3
作者：
Hall, Rasheeda K.;Haines, Carol;Bowling, C. Barrett
通讯作者：
Bowling, C. Barrett
影响因子：
4.1
作者：
Chang, Jing;Gao, Yun;Sun, Qian-Mei
通讯作者：
Sun, Qian-Mei