Efficacy of a skeletal muscle-powered dynamic patch: Part 1. Left ventricular assistance.
Efficacy of a skeletal muscle-powered dynamic patch: Part 1. Left ventricular assistance.
复制标题
骨骼肌驱动的动态贴片的功效:第 1 部分。左心室辅助。
DOI:
10.1016/0003-4975(94)00528-f
复制
发表时间:
1995
期刊:
影响因子:
--
通讯作者:
Y. Watanabe
中科院分区:
文献类型:
--
作者:
M. Takahashi;T. Misaki;G. Watanabe;H. Ohtake;Y. Tsunezuka;M. Wada;N. Sakakibara;Y. Matsunaga;M. Kawasuji;Y. Watanabe
In this study, we examined the capability of a skeletal muscle—powered, dynamic patch to provide left ventricular assistance. An actuator was developed that used linear traction power furnished by the latissimus dorsi muscle and liquid as the medium for power transfer. The proximal portion of the muscle was dissected and was reattached to the actuator. The left ventricular apex was excised, and the dynamic patch lined with autologous pericardium was implanted during cardiopulmonary bypass. Hemodynamic studies were performed in 8 dogs after weaning from cardiopulmonary bypass. Muscle stimulation was found to significantly increase the systolic aortic pressure (91.6 versus 112.1 mm Hg; p < 0.01), the mean aortic pressure (65.2 versus 73.0 mm Hg; p < 0.01), and aortic blood flow (0.77 versus 0.92 L/min; p < 0.01). The left atrial pressure decreased from 17.9 to 16.6 mm Hg (p < 0.01). This “hybrid” left ventricular assist device possesses notable clinical advantages because of its remarkable efficacy in assisting circulation. Further experimental studies using preconditioned skeletal muscle are necessary to assess the long-term effects of this technique.
登录
查看更多内容
DOI:
10.1016/0003-4975(92)91392-m
发表时间:
1992
期刊:
The Annals of thoracic surgery
影响因子:
--
作者:
Hooper,TL;Niinami,H;Hammond,RL;Lu,H;Ruggiero,R;Pochettino,A;Stephenson,LW
通讯作者:
Stephenson,LW
DOI:
--
发表时间:
1987
期刊:
The Journal of thoracic and cardiovascular surgery
影响因子:
--
作者:
Acker,MA;Anderson,WA;Hammond,RL;Chin,AJ;Buchanan,JW;Morse,CC;Kelly,AM;Stephenson,LW
通讯作者:
Stephenson,LW
DOI:
--
发表时间:
1982
期刊:
Transactions - American Society for Artificial Internal Organs
影响因子:
--
作者:
Kyo,S;LaRaia,PJ;Levine,FH;Austen,WG;Buckley,MJ
通讯作者:
Buckley,MJ
影响因子:
37.8
作者:
Anderson,WA;Andersen,JS;Acker,MA;Hammond,RL;Chin,AJ;Douglas,PS;Khalafalla,AS;Salmons,S;Stephenson,LW
通讯作者:
Stephenson,LW
DOI:
--
发表时间:
1992
期刊:
The Journal of thoracic and cardiovascular surgery
影响因子:
--
作者:
Geddes,LA;Badylak,SF;Tacker,WA;Janas,W
通讯作者:
Janas,W