Intestinal development and differentiation.

Intestinal development and differentiation.
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DOI:
10.1016/j.yexcr.2011.09.006
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发表时间:
2011-11-15
影响因子:
3.7
通讯作者:
Shroyer, Noah F.
Shroyer, Noah F.
中科院分区:
医学3区
文献类型:
--
作者:
Noah, Taeko K.;Donahue, Bridgitte;Shroyer, Noah F.

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在这篇综述中,我们提出了一个概述肠发育和肠上皮细胞分化。综述分为两部分:第一部分总结了小肠和大肠的器官发生,包括内胚层和早期胚胎发育中的肠管形成,绒毛形态发生和隐窝形成。第二节回顾了肠上皮细胞的命运和分化的每种类型的细胞。生长因子和转录网络调节这些发展过程进行了总结。
In this review, we present an overview of intestinal development and cellular differentiation of the intestinal epithelium. The review is separated into two sections: Section one summarizes organogenesis of the small and large intestines, including endoderm and gut tube formation in early embryogenesis, villus morphogenesis, and crypt formation. Section two reviews cell fate specification and differentiation of each cell type within the intestinal epithelium. Growth factor and transcriptional networks that regulate these developmental processes are summarized.
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