Television viewing and risk of type 2 diabetes, cardiovascular disease, and all-cause mortality: a meta-analysis.
Television viewing and risk of type 2 diabetes, cardiovascular disease, and all-cause mortality: a meta-analysis.
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DOI：
10.1001/jama.2011.812
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发表时间：
2011-06-15
影响因子：
120.7
通讯作者：
Hu, Frank B.
中科院分区：
文献类型：
--
作者：
Grontved, Anders;Hu, Frank B.
长时间看电视是工业化国家中最普遍和普遍的久坐行为，并与发病率和死亡率相关。然而，尚未对已发表的研究进行系统和定量评估。对所有前瞻性队列研究进行荟萃分析，以确定看电视与2型糖尿病、致死性或非致死性心血管疾病和全因死亡率风险之间的关联。通过无限制地检索1970年至2011年3月的MEDLINE数据库和1974年至2011年3月的EMBASE数据库，并通过审查检索到的文章的参考文献列表，确定了相关研究。纳入了队列研究，这些研究报告了相关性的相对风险估计值和95%置信区间（CI）。数据由每位作者独立提取，并使用随机效应模型获得相关性的汇总估计值。在纳入的8项研究中，4项报告了2型糖尿病的结果（175 938例受试者;在110万人-年的随访期间发生了6428例事件），4例报告了致死性或非致死性心血管疾病（34253人; 1052例事件病例），3例报告了全因死亡（26509人;在202353人-年随访期间死亡1879例）。每天每2小时看电视的合并相对风险为2型糖尿病1.20（95%CI，1.14-1.27），致死性或非致死性心血管疾病1.15（95%CI，1.06-1.23），全因死亡率1.13（95%CI，1.07-1.18）。虽然看电视的时间与2型糖尿病和心血管疾病的风险之间存在线性关系，但每天看电视时间超过3小时，全因死亡的风险似乎会增加。每天每2小时看电视的估计绝对风险差异为每年每10万人中有176例2型糖尿病，每年每10万人中有38例致命性心血管疾病，每年每10万人中有104例全因死亡。长时间看电视与2型糖尿病、心血管疾病和全因死亡率的风险增加有关。
Prolonged television (TV) viewing is the most prevalent and pervasive sedentary behavior in industrialized countries and has been associated with morbidity and mortality. However, a systematic and quantitative assessment of published studies is not available. To perform a meta-analysis of all prospective cohort studies to determine the association between TV viewing and risk of type 2 diabetes, fatal or nonfatal cardiovascular disease, and all-cause mortality. Relevant studies were identified by searches of the MEDLINE database from 1970 to March 2011 and the EMBASE database from 1974 to March 2011 without restrictions and by reviewing reference lists from retrieved articles. Cohort studies that reported relative risk estimates with 95% confidence intervals (CIs) for the associations of interest were included. Data were extracted independently by each author and summary estimates of association were obtained using a random-effects model. Of the 8 studies included, 4 reported results on type 2 diabetes (175 938 individuals; 6428 incident cases during 1.1 million person-years of follow-up), 4 reported on fatal or nonfatal cardiovascular disease (34 253 individuals; 1052 incident cases), and 3 reported on all-cause mortality (26 509 individuals; 1879 deaths during 202 353 person-years of follow-up). The pooled relative risks per 2 hours of TV viewing per day were 1.20 (95% CI, 1.14-1.27) for type 2 diabetes, 1.15 (95% CI, 1.06-1.23) for fatal or nonfatal cardiovascular disease, and 1.13 (95% CI, 1.07-1.18) for all-cause mortality. While the associations between time spent viewing TV and risk of type 2 diabetes and cardiovascular disease were linear, the risk of all-cause mortality appeared to increase with TV viewing duration of greater than 3 hours per day. The estimated absolute risk differences per every 2 hours of TV viewing per day were 176 cases of type 2 diabetes per 100 000 individuals per year, 38 cases of fatal cardiovascular disease per 100 000 individuals per year, and 104 deaths for all-cause mortality per 100 000 individuals per year. Prolonged TV viewing was associated with increased risk of type 2 diabetes, cardiovascular disease, and all-cause mortality.
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