Genenames.org: the HGNC and VGNC resources in 2017.
Genenames.org: the HGNC and VGNC resources in 2017.
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DOI：
10.1093/nar/gkw1033
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发表时间：
2017-01-04
影响因子：
14.9
通讯作者：
Bruford EA
中科院分区：
文献类型：
--
作者：
Yates B;Braschi B;Gray KA;Seal RL;Tweedie S;Bruford EA
总部设在欧洲生物信息学研究所的雨果基因命名委员会(HGNC)为人类基因分配了独特的符号和名称。目前，HGNC数据库包含近40,000个已获批准的基因符号，其中超过19,000个代表蛋白质编码基因。除了命名基因组位置外，我们还根据共同的特征，如同源性、功能或表型，手动将基因归类为家族集。我们最近更新了我们的基因家族资源，并引入了新的改进的可视化，可以在我们的主要网站http://www.genenames.org.上与我们的基因符号报告一起看到2016年，我们扩大了职权范围，成立了脊椎动物基因命名委员会(VGNC)，负责为缺乏专门命名小组的脊椎动物物种命名。利用黑猩猩基因组作为一个试点项目，我们已经批准了黑猩猩14500多个蛋白质编码基因的符号和名称，并开发了一个新的网站http://vertebrate.genenames.org来发布这些数据。在这里，我们回顾了我们的在线数据和资源，特别关注过去两年来的改进和新的发展。
The HUGO Gene Nomenclature Committee (HGNC) based at the European Bioinformatics Institute (EMBL-EBI) assigns unique symbols and names to human genes. Currently the HGNC database contains almost 40 000 approved gene symbols, over 19 000 of which represent protein-coding genes. In addition to naming genomic loci we manually curate genes into family sets based on shared characteristics such as homology, function or phenotype. We have recently updated our gene family resources and introduced new improved visualizations which can be seen alongside our gene symbol reports on our primary website http://www.genenames.org. In 2016 we expanded our remit and formed the Vertebrate Gene Nomenclature Committee (VGNC) which is responsible for assigning names to vertebrate species lacking a dedicated nomenclature group. Using the chimpanzee genome as a pilot project we have approved symbols and names for over 14 500 protein-coding genes in chimpanzee, and have developed a new website http://vertebrate.genenames.org to distribute these data. Here, we review our online data and resources, focusing particularly on the improvements and new developments made during the last two years.
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影响因子：
14.9
作者：
Smedley D;Haider S;Durinck S;Pandini L;Provero P;Allen J;Arnaiz O;Awedh MH;Baldock R;Barbiera G;Bardou P;Beck T;Blake A;Bonierbale M;Brookes AJ;Bucci G;Buetti I;Burge S;Cabau C;Carlson JW;Chelala C;Chrysostomou C;Cittaro D;Collin O;Cordova R;Cutts RJ;Dassi E;Di Genova A;Djari A;Esposito A;Estrella H;Eyras E;Fernandez-Banet J;Forbes S;Free RC;Fujisawa T;Gadaleta E;Garcia-Manteiga JM;Goodstein D;Gray K;Guerra-Assunção JA;Haggarty B;Han DJ;Han BW;Harris T;Harshbarger J;Hastings RK;Hayes RD;Hoede C;Hu S;Hu ZL;Hutchins L;Kan Z;Kawaji H;Keliet A;Kerhornou A;Kim S;Kinsella R;Klopp C;Kong L;Lawson D;Lazarevic D;Lee JH;Letellier T;Li CY;Lio P;Liu CJ;Luo J;Maass A;Mariette J;Maurel T;Merella S;Mohamed AM;Moreews F;Nabihoudine I;Ndegwa N;Noirot C;Perez-Llamas C;Primig M;Quattrone A;Quesneville H;Rambaldi D;Reecy J;Riba M;Rosanoff S;Saddiq AA;Salas E;Sallou O;Shepherd R;Simon R;Sperling L;Spooner W;Staines DM;Steinbach D;Stone K;Stupka E;Teague JW;Dayem Ullah AZ;Wang J;Ware D;Wong-Erasmus M;Youens-Clark K;Zadissa A;Zhang SJ;Kasprzyk A
通讯作者：
Kasprzyk A
影响因子：
14.9
作者：
Harrow JL;Steward CA;Frankish A;Gilbert JG;Gonzalez JM;Loveland JE;Mudge J;Sheppard D;Thomas M;Trevanion S;Wilming LG
通讯作者：
Wilming LG
影响因子：
5.8
作者：
Chen, LF;Liu, HF;Friedman, C
通讯作者：
Friedman, C
DOI：
10.1093/bioinformatics/btn615
发表时间：
2009-01-15
期刊：
Bioinformatics (Oxford, England)
影响因子：
--
作者：
Carbon S;Ireland A;Mungall CJ;Shu S;Marshall B;Lewis S;AmiGO Hub;Web Presence Working Group
通讯作者：
Web Presence Working Group
影响因子：
14.9
作者：
UniProt Consortium
通讯作者：
UniProt Consortium