UniProt: a hub for protein information.

UniProt: a hub for protein information.
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DOI:
10.1093/nar/gku989
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发表时间:
2015-01
影响因子:
14.9
通讯作者:
UniProt Consortium
UniProt Consortium
中科院分区:
生物学2区
文献类型:
--
作者:
UniProt Consortium

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UniProt是蛋白质序列及其注释的重要集合,在过去的一年中,其大小翻了一番,达到8000万个序列。序列的这种增长促使UniProt登录号空间从6个字符扩展到10个字符。越来越多的新序列与数据库中已经存在的序列相同,其中大多数序列来自基因组测序项目。我们已经创建了一个新的蛋白质组标识符,可以唯一识别物种和菌株或亚种的特定组装,以帮助用户跟踪序列的来源。我们提出了一个新的网站,已设计使用用户体验设计过程。我们已经为UniProt中的所有条目引入了注释分数,以表示关于每个蛋白质已知的相对知识量。这些分数将有助于确定哪些蛋白质是最好的特征和最多的信息进行比较分析。所有UniProt数据都是免费提供的,可在http://www.uniprot.org/网站上查阅。
UniProt is an important collection of protein sequences and their annotations, which has doubled in size to 80 million sequences during the past year. This growth in sequences has prompted an extension of UniProt accession number space from 6 to 10 characters. An increasing fraction of new sequences are identical to a sequence that already exists in the database with the majority of sequences coming from genome sequencing projects. We have created a new proteome identifier that uniquely identifies a particular assembly of a species and strain or subspecies to help users track the provenance of sequences. We present a new website that has been designed using a user-experience design process. We have introduced an annotation score for all entries in UniProt to represent the relative amount of knowledge known about each protein. These scores will be helpful in identifying which proteins are the best characterized and most informative for comparative analysis. All UniProt data is provided freely and is available on the web at http://www.uniprot.org/.
DOI: 10.1021/bi500349e
发表时间: 2014-04-29
期刊: Biochemistry
影响因子: 2.9
作者:
Wichelecki DJ;Froese DS;Kopec J;Muniz JR;Yue WW;Gerlt JA
通讯作者: Gerlt JA
DOI: 10.1093/nar/gkr948
发表时间: 2012-01
影响因子: 14.9
作者:
Hunter S;Jones P;Mitchell A;Apweiler R;Attwood TK;Bateman A;Bernard T;Binns D;Bork P;Burge S;de Castro E;Coggill P;Corbett M;Das U;Daugherty L;Duquenne L;Finn RD;Fraser M;Gough J;Haft D;Hulo N;Kahn D;Kelly E;Letunic I;Lonsdale D;Lopez R;Madera M;Maslen J;McAnulla C;McDowall J;McMenamin C;Mi H;Mutowo-Muellenet P;Mulder N;Natale D;Orengo C;Pesseat S;Punta M;Quinn AF;Rivoire C;Sangrador-Vegas A;Selengut JD;Sigrist CJ;Scheremetjew M;Tate J;Thimmajanarthanan M;Thomas PD;Wu CH;Yeats C;Yong SY
通讯作者: Yong SY
DOI: 10.1093/nar/gks1146
发表时间: 2013-01
影响因子: 14.9
作者:
Hastings J;de Matos P;Dekker A;Ennis M;Harsha B;Kale N;Muthukrishnan V;Owen G;Turner S;Williams M;Steinbeck C
通讯作者: Steinbeck C
DOI: 10.1093/nar/gkr1048
发表时间: 2012-01
影响因子: 14.9
作者:
Dimmer EC;Huntley RP;Alam-Faruque Y;Sawford T;O'Donovan C;Martin MJ;Bely B;Browne P;Mun Chan W;Eberhardt R;Gardner M;Laiho K;Legge D;Magrane M;Pichler K;Poggioli D;Sehra H;Auchincloss A;Axelsen K;Blatter MC;Boutet E;Braconi-Quintaje S;Breuza L;Bridge A;Coudert E;Estreicher A;Famiglietti L;Ferro-Rojas S;Feuermann M;Gos A;Gruaz-Gumowski N;Hinz U;Hulo C;James J;Jimenez S;Jungo F;Keller G;Lemercier P;Lieberherr D;Masson P;Moinat M;Pedruzzi I;Poux S;Rivoire C;Roechert B;Schneider M;Stutz A;Sundaram S;Tognolli M;Bougueleret L;Argoud-Puy G;Cusin I;Duek-Roggli P;Xenarios I;Apweiler R
通讯作者: Apweiler R
查找超过270个孤儿酶的序列。
DOI: 10.1371/journal.pone.0097250
发表时间: 2014
期刊: PloS one
影响因子: 3.7
作者:
Shearer AG;Altman T;Rhee CD
通讯作者: Rhee CD