The Roles of Type I Interferon in Bacterial Infection.
The Roles of Type I Interferon in Bacterial Infection.
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DOI:
10.1016/j.chom.2016.05.016
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发表时间:
2016-06-08
影响因子:
30.3
通讯作者:
Cheng G
中科院分区:
文献类型:
--
作者:
Boxx GM;Cheng G
Type I interferons (IFNs) are pleiotropic cytokines well recognized for their role in the induction of a potent anti-viral gene program essential for host defense against viruses. They also modulate innate and adaptive immune responses. However, the role of type I IFNs in host defense against bacterial infections is enigmatic. Depending on the bacterium, they exert seemingly opposite and capricious functions. In this review we summarize the effect of type I IFNs on specific bacterial infections and highlight the effector mechanisms regulated by type I IFNs in an attempt to elucidate new avenues to understanding their role.
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影响因子:
11.1
作者:
Cao, Ju;Wang, Dongsheng;Xu, Fang;Gong, Yi;Wang, Hong;Song, Zixin;Li, Dageng;Zhang, Hua;Li, Dairong;Zhang, Liping;Xia, Yun;Xu, Huajian;Lai, Xaiofei;Lin, Shihui;Zhang, Xuemei;Ren, Guosheng;Dai, Yubing;Yin, Yibing
通讯作者:
Yin, Yibing
影响因子:
64.8
作者:
通讯作者:
--
DOI:
10.1038/mtm.2014.5
发表时间:
2014
期刊:
Molecular therapy. Methods & clinical development
影响因子:
--
作者:
通讯作者:
--
影响因子:
4.4
作者:
Eigenbrod, Tatjana;Pelka, Karin;Dalpke, Alexander H.
通讯作者:
Dalpke, Alexander H.
影响因子:
11.4
作者:
Abdullah, Zeinab;Schlee, Martin;Knolle, Percy A.
通讯作者:
Knolle, Percy A.