Blood glucose measurement in vivo using hollow-fiber based, mid-infrared ATR probe with multi-reflection prism

Blood glucose measurement in vivo using hollow-fiber based, mid-infrared ATR probe with multi-reflection prism
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使用带有多反射棱镜的中空纤维中红外 ATR 探头进行体内血糖测量

DOI:
10.1117/12.2216652
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发表时间:
2016
影响因子:
3.2
通讯作者:
Y. Matsuura
Y. Matsuura
中科院分区:
工程技术3区
文献类型:
--
作者:
S. Kino;Suguru Omori;Y. Matsuura

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一种衰减全反射(ATR),中红外光谱系统,包括中空光纤,梯形多反射ATR棱镜,和传统的FT-IR光谱仪已被开发用于测量血糖水平。由于中空光纤的低传输损耗和高柔性,该系统可以测量人体任何部位的毛细血管接近粘膜表面,如内唇。采用多反射棱镜提高了灵敏度,棱镜接触面宽平,测量重现性好。人体内唇的在体测量结果表明了该系统的可行性,测量误差在20%以内。
An attenuated-total-reflection (ATR), mid-infrared spectroscopy system that consists of hollow optical fibers, a trapezoidal multi-reflection ATR prism, and a conventional FT-IR spectrometer has been developed to measure blood glucose levels. Owing to the low transmission loss and high flexibility of the hollow-optical fiber, the system can measure any sites of the human body where blood capillaries are close to the surface of mucosa, such as inner lips. Using a multi-reflection prism brought about higher sensitivity, and the flat and wide contact surface of the prism resulted in higher measurement reproducibility. The results of in-vivo measurement of human inner lips showed the feasibility of the proposed system, and the measurement errors were within 20%.
DOI: 10.1117/1.1920212
发表时间: 2005-05-01
影响因子: 3.5
作者:
Enejder, AMK;Scecina, TG;Feld, MS
通讯作者: Feld, MS