Sterols in asthma.
Sterols in asthma.
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DOI:
10.1016/j.it.2022.08.003
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发表时间:
2022-10
影响因子:
16.8
通讯作者:
Britt Jr, Rodney D.
中科院分区:
文献类型:
--
作者:
Guerau-de-Arellano, Mireia;Britt Jr, Rodney D.
While sterols regulate immune processes key to the pathogenesis of asthma, inhibition of sterols with statin drugs has shown conflicting results in human asthma. Here, a novel understanding of the impact of sterols on type 17 immune responses and asthma lead us to hypothesize that sterols and statins may be relevant to severe asthma endotypes with neutrophil infiltration.
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