Therapy of Pulmonary Edema
Therapy of Pulmonary Edema
复制标题
肺水肿的治疗
DOI：
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
K. Brigham
中科院分区：
文献类型：
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作者：
K. Brigham
对肺水肿患者进行治疗的任何理由都取决于治疗终点。正如本卷前面讨论的，除了水肿(即肺部液体过多)外，还有几种肺功能异常，可能是导致低氧血症的主要原因，因此，如果氧合是用于评估治疗有效性的变量，那么减少水肿量的手法可能看起来并不有效。在某些情况下，可能改善呼吸道功能或改变肺血管功能的药物很可能是治疗性的，即使它们不能改善氧合或减少水肿量。本文将只讨论旨在减少肺部水肿量或防止进一步积聚水肿液的治疗方法。本讨论将根据已知的肺水肿发病机制提出理论基础，在前几篇文章中讨论过。
Any rationale for therapy in patients with pulmonary edema depends on the therapeutic endpoint. As discussed earlier in this volume, there are several abnormalities of lung function, in addition to edema (that is, excess fluid in the lungs), that may be major contributors to the hypoxemia, so that if oxygenation is the variable used to assess the effectiveness of therapy, manipulations which reduce the amount of edema may not appear efficacious. It may well be that drugs that may improve airway function or alter functions of the pulmonary vasculature are therapeutic in some conditions even though they do not improve oxygenation or reduce the amount of edema. This article will deal only with therapies aimed at reducing the amount of edema in the lungs or preventing further accumulation of edema fluid. The discussion will present rationales based on what is known about the pathogenesis of pulmonary edema, discussed in the previous articles.
影响因子：
15.9
作者：
HEFLIN, AC;BRIGHAM, KL
通讯作者：
BRIGHAM, KL