Cellulose nanocrystals as biobased nucleation agents in poly-L-lactide scaffold: Crystallization behavior and mechanical properties
Cellulose nanocrystals as biobased nucleation agents in poly-L-lactide scaffold: Crystallization behavior and mechanical properties
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纤维素纳米晶体作为聚-L-丙交酯支架中生物基成核剂：结晶行为和机械性能
DOI：
10.1016/j.polymertesting.2020.106458
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发表时间：
2020-05
期刊：
影响因子：
5.1
通讯作者：
Wang Guoyong
中科院分区：
文献类型：
--
作者：
Shuai Cijun;Yuan Xun;Yang Wenjing;Peng Shuping;He Chongxian;Feng Pei;Qi Fangwei;Wang Guoyong
聚合物支架的机械强度与其结晶度密切相关。本工作采用选择性激光烧结法制备了聚L-丙交酯(PLLA)支架，并将其引入纤维素纳米晶中，以提高材料的力学性能。CnC含有大量的羟基，这些羟基可能与PLLA分子链形成氢键。氢键通过非均相成核剂诱导PLLA链有序排列，从而提高结晶速率和结晶度。结果表明，添加3wt%CNC的PLLA支架的抗压强度、压缩弹性模量、拉伸强度、拉伸弹性模量和维氏硬度分别提高了191%、351%、34%、83.5%和56%。可喜的是，与PLLA相比，PLLA/CNC支架不仅具有更好的亲水性，而且降解速度更快。体外细胞培养实验表明，PLLA/CNC支架具有良好的生物相容性，能够支持细胞的黏附、增殖和分化。以上结果表明，PLLA/CNC复合支架可能是一种潜在的骨修复替代材料。
The mechanical strength of polymer scaffold is closely related to its crystallinity. In this work, cellulose nanocrystals (CNC) were incorporated into poly-l-lactide (PLLA) scaffold which was fabricated by selective laser sintering, aiming to improve the mechanical properties. CNC possesses numerous hydroxyl groups which might form hydrogen bond with PLLA molecular chains. The hydrogen bond induces the ordered arrangement of PLLA chain by using CNC as heterogeneous nucleating agent, thereby increasing crystallization rate and crystallinity. Results showed that PLLA scaffolds with 3 wt% CNC resulted in 191%, 351%, 34%, 83.5%, 56% increase in compressive strength, compressive modulus, tensile strength, tensile modulus and Vickers hardness, respectively. Encouragingly, with the incorporation of hydrophilic CNC, the PLLA/CNC scaffolds showed not only better hydrophilicity, but also faster degradation than PLLA.In vitrocell culture studies proved that the PLLA/CNC scaffolds were biocompatible and capable of supporting cell adhesion, proliferation and differentiation. The above results indicated that the PLLA/CNC scaffolds may therefore be a potential replacement in bone repair.
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DOI：
10.1088/1757-899x/213/1/012034
发表时间：
2017-06
期刊：
IOP Conference Series: Materials Science and Engineering
影响因子：
--
作者：
Y. Cai
通讯作者：
Y. Cai
通过皮克林乳液工艺改进性能的可生物降解再生纤维素分散复合材料
影响因子：
11.2
作者：
Yunchong Zhang;Yang Jiang;Lei Han;Bijia Wang;Hong Xu;Yi Zhong;Linping Zhang;Zhiping Mao;Xiaofeng Sui
通讯作者：
Xiaofeng Sui
影响因子：
5.5
作者：
Barrau, S.;Vanmansart, C.;Seguela, R.
通讯作者：
Seguela, R.
影响因子：
3.2
作者：
Yan-Hua Cai;Lisha Zhao;L. Tian
通讯作者：
Yan-Hua Cai;Lisha Zhao;L. Tian
影响因子：
4.6
作者：
H. Tsuji;Hiroki Takai;S. Saha
通讯作者：
H. Tsuji;Hiroki Takai;S. Saha