Age and stage as determinants of treatment for oral cavity and oropharyngeal cancers in the elderly.
Age and stage as determinants of treatment for oral cavity and oropharyngeal cancers in the elderly.
复制标题
年龄和阶段是老年人口腔和口咽癌治疗的决定因素。
DOI：
10.1016/j.oraloncology.2014.07.008
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发表时间：
2014-10
期刊：
影响因子：
4.8
通讯作者：
Hollenbeak, Christopher S.
中科院分区：
文献类型：
--
作者：
Goldenberg, David;Mackley, Heath;Koch, Wayne;Bann, Darrin V.;Schaefer, Eric W.;Hollenbeak, Christopher S.
我们调查了口腔和口咽（OC&OP）癌症的治疗选择，以了解影响治疗选择的因素。我们研究了7，023名66岁的患者，他们使用SEER-Medicare数据诊断为第一次原发性OC&OP癌症。多项逻辑回归用于模拟治疗选择，控制其他因素。大多数OC癌患者仅接受手术治疗（56.5%）;大多数OP癌患者接受化疗和放疗（28.9%）。年龄、分期和部位是治疗选择的最重要预测因素。随着年龄从70岁增加到81岁（四分位距），治疗转向单独手术（OR=1.26; CI：1.08-1.46）和不治疗（OR=1.5，95%CI：1.25-1.80），远离联合手术、放疗和化疗治疗。年龄、分期和部位是OC&OP癌症患者治疗选择的最重要决定因素。年龄和分期的增加使治疗转向非手术治疗，根本不治疗。
We investigate treatment selection for oral cavity and oropharyngeal (OC&OP) cancers to understand factors that influence treatment selection. We studied 7,023 patients, 66 years, diagnosed with a first primary OC&OP cancer using SEER-Medicare data. Multinomial logistic regression was to model treatment selection, controlling for other factors. Most patients with OC cancer were treated with surgery alone (56.5%); most patients with OP cancer were treated with chemotherapy and radiation (28.9%). Age, stage and site were the most important predictors of treatment selection. As age increased from 70 to 81 (the interquartile range), treatment shifted toward surgery alone (OR=1.26; CI: 1.08-1.46) and no treatment (OR=1.5, 95% CI: 1.25-1.80), and away from combined surgery, radiation and treatments involving chemotherapy. Age, stage, and site are the most important determinants of treatment selection for patients with OC&OP cancers. Increasing age and stage drive treatment toward non-surgical options and no treatment at all.
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影响因子：
6.2
作者：
Lacy, PD;Kennedy, JT;Piccirillo, JF
通讯作者：
Piccirillo, JF
影响因子：
3
作者：
Elixhauser, A;Steiner, C;Coffey, RN
通讯作者：
Coffey, RN
影响因子：
120.7
作者：
SAMET, J;HUNT, WC;GOODWIN, JS
通讯作者：
GOODWIN, JS
影响因子：
2.6
作者：
Hu, Melissa;Ampil, Fred;Nathan, Cherie-Ann O.
通讯作者：
Nathan, Cherie-Ann O.
DOI：
10.4317/medoral.18772
发表时间：
2013-03-01
期刊：
Medicina oral, patologia oral y cirugia bucal
影响因子：
--
作者：
Huang SH;O'Sullivan B
通讯作者：
O'Sullivan B