Manipulation and confinement of single particles using fluid flow.
Manipulation and confinement of single particles using fluid flow.
复制标题
使用流体流对单个颗粒进行操纵和限制。
DOI:
10.1021/nl4008437
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发表时间:
2013-06-12
期刊:
影响因子:
10.8
通讯作者:
Schroeder CM
中科院分区:
文献类型:
--
作者:
Tanyeri M;Schroeder CM
High precision control of micro- and nanoscale objects in aqueous media is an essential technology for nanoscience and engineering. Existing methods for particle trapping primarily depend on optical, magnetic, electrokinetic, and acoustic fields. In this work, we report a new hydrodynamic flow based approach that allows for fine-scale manipulation and positioning of single micro- and nanoscale particles using automated fluid flow. As a proof-of-concept, we demonstrate trapping and two-dimensional manipulation of 500 nm and 2.2 μm diameter particles with a positioning precision as small as 180 nm during confinement. By adjusting a single flow parameter, we further show that the shape of the effective trap potential can be efficiently controlled. Finally, we demonstrate two distinct features of the flow-based trapping method, including isolation of a single particle from a crowded particle solution and active control over the surrounding medium of a trapped object. The 2-D flow-based trapping method described here further expands the micro/nanomanipulation toolbox for small particles and holds strong promise for applications in biology, chemistry, and materials research.
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