The association between coffee consumption and bladder cancer in the bladder cancer epidemiology and nutritional determinants (BLEND) international pooled study.
The association between coffee consumption and bladder cancer in the bladder cancer epidemiology and nutritional determinants (BLEND) international pooled study.
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膀胱癌流行病学和营养决定因素（BLEND）国际汇总研究中咖啡摄入量与膀胱癌之间的关联。
DOI：
10.1007/s10552-019-01191-1
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发表时间：
2019-08
期刊：
影响因子：
--
通讯作者：
Zeegers MP
中科院分区：
文献类型：
--
作者：
Yu EY;Wesselius A;van Osch F;Stern MC;Jiang X;Kellen E;Lu CM;Pohlabeln H;Steineck G;Marshall J;Allam MF;La Vecchia C;Johnson KC;Benhamou S;Zhang ZF;Bosetti C;Taylor JA;Zeegers MP
Inconsistent results for coffee consumption and bladder cancer (BC) risk have been shown in epidemiological studies. This research aims to increase the understanding of the association between coffee consumption and BC risk by bringing together worldwide case–control studies on this topic. Data were collected from 13 case–control comprising of 5,911 cases and 16,172 controls. Pooled multivariate odds ratios (ORs), with corresponding 95% confidence intervals (CIs), were obtained using multilevel logistic regression models. Furthermore, linear dose–response relationships were examined using fractional polynomial models. No association of BC risk was observed with coffee consumption among smokers. However, after adjustment for age, gender, and smoking, the risk was significantly increased for never smokers (ever vs. never coffee consumers: ORmodel2 1.30, 95% CI 1.06–1.59; heavy (> 4 cups/day) coffee consumers vs. never coffee consumers: ORmodel2 1.52, 95% CI 1.18–1.97, p trend = 0.23). In addition, dose–response analyses, in both the overall population and among never smokers, also showed a significant increased BC risk for coffee consumption of more than four cups per day. Among smokers, a significant increased BC risk was shown only after consumption of more than six cups per day. This research suggests that positive associations between coffee consumption and BC among never smokers but not smokers.
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影响因子：
6.7
作者：
Benowitz, NL;Peng, M;Jacob, P
通讯作者：
Jacob, P
影响因子：
10.4
作者：
Ames, BN;Gold, LS
通讯作者：
Gold, LS
影响因子：
7.7
作者：
Bjørngaard JH;Nordestgaard AT;Taylor AE;Treur JL;Gabrielsen ME;Munafò MR;Nordestgaard BG;Åsvold BO;Romundstad P;Davey Smith G
通讯作者：
Davey Smith G
影响因子：
8.4
作者：
DAVANZO, B;LAVECCHIA, C;BUTTINO, I
通讯作者：
BUTTINO, I
影响因子：
5.4
作者：
Bracken, MB;Triche, E;Leaderer, BP
通讯作者：
Leaderer, BP