Understanding the physiological roles of the neuronal calcium sensor proteins.
Understanding the physiological roles of the neuronal calcium sensor proteins.
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DOI:
10.1186/1756-6606-5-2
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发表时间:
2012-01-23
期刊:
影响因子:
3.6
通讯作者:
Haynes LP
中科院分区:
文献类型:
--
作者:
Burgoyne RD;Haynes LP
Calcium signalling plays a crucial role in the control of neuronal function and plasticity. Changes in neuronal Ca2+ concentration are detected by Ca2+-binding proteins that can interact with and regulate target proteins to modify their function. Members of the neuronal calcium sensor (NCS) protein family have multiple non-redundant roles in the nervous system. Here we review recent advances in the understanding of the physiological roles of the NCS proteins and the molecular basis for their specificity.
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影响因子:
34.7
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