A higher number of TMS-elicited MEP from a combined hotspot improves intra- and inter-session reliability of the upper limb muscles in healthy individuals.

A higher number of TMS-elicited MEP from a combined hotspot improves intra- and inter-session reliability of the upper limb muscles in healthy individuals.
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DOI:
10.1371/journal.pone.0047582
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发表时间:
2012
期刊:
影响因子:
3.7
通讯作者:
Jaberzadeh S
Jaberzadeh S
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Bastani A;Jaberzadeh S

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我们的目的是使用经颅磁刺激 (TMS) 确定诱发运动诱发电位 (MEP) 的数量,这些诱发电位 (MEP) 可以为桡侧伸肌 (ECR) 和第一背侧骨间肌 (FDI) 带来最高的训练内和训练间可靠性。十二名健康受试者在不同的两天参加了这项研究。使用 Magstim 2002 触发单脉冲磁刺激,以从感兴趣的肌肉中获取 MEP,受试者处于放松的位置。 MEP 响应的可靠性在三组(每组 5、10 和 15 次试验)中进行了调查。使用组内相关系数 (ICC) 评估 MEP 幅度和延迟的会话内和会话间可靠性。重复测量方差分析和配对 t 检验显示 MEP 幅度和潜伏期测量没有显着的时间效应 (P>0.05)。 ICC 表明 ECR 和 FDI 肌肉的 MEP 振幅(分别为 0.77 至 0.99、0.90 至 0.99)和潜伏期(分别为 0.80 至 1.00、0.75 至 0.97)具有较高的会话内可靠性。 MEP 的振幅也具有较高的会话间可靠性(分别为 0.84 至 0.97、0.88 至 0.93),其潜伏期也是如此(分别为 0.80 至 0.90、0.75 至 0.97)。 10 次和 15 次试验的组块获得了最高的组内和组间可靠性。我们的数据表明,应使用至少 10 名欧洲议会议员采用“组合热点”刺激技术进行会话内和会话间比较,以确保最高的可靠性。
We aimed to determine, using transcranial magnetic stimulation (TMS), the number of elicited motor evoked potentials (MEPs) that induces the highest intra- and inter-sessions reliability for the extensor carpi radialis (ECR) and first dorsal interosseus (FDI) muscles. Twelve healthy subjects participated in this study on two separate days. Single pulse magnetic stimuli were triggered with Magstim 2002 to obtain MEPs from the muscles of interest, with the subjects in a relaxed position. Reliability of MEP responses was investigated in three blocks of 5, 10 and 15 trials. The intra- and inter-session reliability of the MEPs' amplitudes and latencies were assessed using intraclass correlation coefficients (ICCs). Repeated measures ANOVA and paired t-tests revealed no significant time effect in the MEP amplitude and latency measurements (P>0.05). The ICCs indicated high intra-session reliability in the MEPs' amplitudes for the ECR and FDI muscles (0.77 to 0.99, 0.90 to 0.99, respectively) and latency (0.80 to 1.00, 0.75 to 0.97, respectively). The MEPs' amplitudes also had high inter-session reliability (0.84 to 0.97, 0.88 to 0.93, respectively), as did their latency (0.80 to 0.90, 0.75 to 0.97, respectively). Highest intra- and inter-session reliability was achieved for blocks of 10 and 15 trials. Our data suggest that intra- and inter-session comparisons should be performed using at least 10 MEPs in “combined hotspot” stimulation technique to ensure highest reliability.
DOI: 10.1080/00207450701668020
发表时间: 2008-02-01
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作者:
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