The role of the blood transcriptome in innate inflammation and stroke.
The role of the blood transcriptome in innate inflammation and stroke.
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DOI:
10.1111/j.1749-6632.2010.05731.x
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发表时间:
2010-10
影响因子:
5.2
通讯作者:
Tanriverdi K
中科院分区:
文献类型:
--
作者:
Freedman JE;Vitseva O;Tanriverdi K
Cerebrovascular disease is a major cause of death and disability, with a poorer outcome in patients having select risk factors including diabetes and hypertension. Risk factors and the state of cerebral ischemia-reperfusion associated with cerebrovascular occlusion are known to cause inflammatory changes. These events and the inflammatory state are reflected by transcript changes in various components of the blood and can be specifically measured. By defining these changes, new insight into cerebrovascular disease and its therapeutics is being achieved.
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10.1124/jpet.105.089987
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