Fe-S proteins that regulate gene expression.
Fe-S proteins that regulate gene expression.
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DOI:
10.1016/j.bbamcr.2014.11.018
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发表时间:
2015-06
影响因子:
5.1
通讯作者:
Kiley, Patricia J.
中科院分区:
文献类型:
--
作者:
Mettert, Erin L.;Kiley, Patricia J.
Iron-sulfur (Fe-S) cluster containing proteins that regulate gene expression are present in most organisms. The innate chemistry of their Fe-S cofactors makes these regulatory proteins ideal for sensing environmental signals, such as gases (e.g. O2 and NO), levels of Fe and Fe-S clusters, reactive oxygen species, and redox cycling compounds, to subsequently mediate an adaptive response. Here we review the recent findings that have provided invaluable insight into the mechanism and function of these highly significant Fe-S regulatory proteins.
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