Everything is connected: Inference and attractors in delusions.
Everything is connected: Inference and attractors in delusions.
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一切都是相连的:错觉中的推理和吸引子。
DOI:
10.1016/j.schres.2021.07.032
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发表时间:
2022-07
影响因子:
4.5
通讯作者:
Parr, Thomas
中科院分区:
文献类型:
--
作者:
Adams, Rick A.;Vincent, Peter;Benrimoh, David;Friston, Karl J.;Parr, Thomas
关键词:
Delusions are, by popular definition, false beliefs that are held with certainty and resistant to contradictory evidence. They seem at odds with the notion that the brain at least approximates Bayesian inference. This is especially the case in schizophrenia, a disorder thought to relate to decreased – rather than increased – certainty in the brain's model of the world. We use an active inference Markov decision process model (a Bayes-optimal decision-making agent) to perform a simple task involving social and non-social inferences. We show that even moderate changes in some model parameters – decreasing confidence in sensory input and increasing confidence in states implied by its own (especially habitual) actions – can lead to delusions as defined above. Incorporating affect in the model increases delusions, specifically in the social domain. The model also reproduces some classic psychological effects, including choice-induced preference change, and an optimism bias in inferences about oneself. A key observation is that no change in a single parameter is both necessary and sufficient for delusions; rather, delusions arise due to conditional dependencies that create ‘basins of attraction’ which trap Bayesian beliefs. Simulating the effects of antidopaminergic antipsychotics – by reducing the model's confidence in its actions – demonstrates that the model can escape from these attractors, through this synthetic pharmacotherapy.
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DOI:
10.1177/2167702620951553
发表时间:
2021-01
期刊:
Clinical psychological science : a journal of the Association for Psychological Science
影响因子:
--
作者:
Bell V;Raihani N;Wilkinson S
通讯作者:
Wilkinson S
影响因子:
4
作者:
Chen AG;Benrimoh D;Parr T;Friston KJ
通讯作者:
Friston KJ
影响因子:
3
作者:
Kwak S;Huh N;Seo JS;Lee JE;Han PL;Jung MW
通讯作者:
Jung MW
影响因子:
6.6
作者:
Ben-Zeev, Dror;Ellington, Kemp;Granholm, Eric
通讯作者:
Granholm, Eric
DOI:
10.1162/cpsy_a_00022
发表时间:
2018-12-01
期刊:
Computational psychiatry (Cambridge, Mass.)
影响因子:
--
作者:
Benrimoh, David;Parr, Thomas;Friston, Karl
通讯作者:
Friston, Karl