Dietary therapy in abdominal aortic aneurysm - Insights from clinical and experimental studies.
Dietary therapy in abdominal aortic aneurysm - Insights from clinical and experimental studies.
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DOI：
10.3389/fcvm.2022.949262
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发表时间：
2022
影响因子：
3.6
通讯作者：
Wang, Bowen
中科院分区：
文献类型：
--
作者：
Yin, Li;Gregg, Alexander Christopher;Riccio, Alessandra Marie;Hoyt, Nicholas;Islam, Zain Hussain;Ahn, Jungeun;Le, Quang;Patel, Paranjay;Zhang, Mengxue;He, Xinran;McKinney, Matthew;Kent, Eric;Wang, Bowen
关键词：
腹主动脉瘤（AAA）是一种常见的血管疾病，破裂后死亡率高。尽管其在老年人群中普遍存在，但治疗选择仍然有限;侵入性手术修复虽然有风险，但却是唯一具有临床获益的治疗干预措施。长期以来，饮食因素一直被认为与AAA风险密切相关，最近出现的饮食疗法是实现广泛疾病非侵入性管理的有希望的途径。然而，饮食疗法在AAA中的作用仍然难以捉摸。在这篇文章中，我们将总结最近的临床和临床前的努力，了解各种饮食模式和治疗方法在AAA的治疗和机制的影响。
Abdominal aortic aneurysm (AAA) is a prevalent vascular disease with high mortality rates upon rupture. Despite its prevalence in elderly populations, there remain limited treatment options; invasive surgical repair, while risky, is the only therapeutic intervention with proven clinical benefits. Dietary factors have long been suggested to be closely associated with AAA risks, and dietary therapies recently emerged as promising avenues to achieve non-invasive management of a wide spectrum of diseases. However, the role of dietary therapies in AAA remains elusive. In this article, we will summarize the recent clinical and pre-clinical efforts in understanding the therapeutic and mechanistic implications of various dietary patterns and therapeutic approaches in AAA.
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