Inhibitory Effect of Antibacterial Resin Composite against Streptococcus mutans
Inhibitory Effect of Antibacterial Resin Composite against Streptococcus mutans
复制标题
抗菌树脂复合材料对变形链球菌的抑制作用
作者：
M. Tanagawa;K. Yoshida;Sohkichi Matsumoto;T. Yamada;Mitsuru Atsuta
具有抗菌活性的牙科树脂复合材料可用于预防修复体周围常见的继发龋。三种银载抗菌材料（Novaron、Ameritop 和 AIS）可抑制主要口腔病原体变形链球菌的生长。 Novaron、Ameritop 和 AIS 悬浮液对变形链球菌的最低抑制量分别为 40、30 和 400 μg/ml。将这些抗菌材料加入到 TEGDMA-UDMA 基光活化树脂复合材料中，并检查了这些复合材料的抗菌活性。含有 5 wt% (N-5) 或更多 Novaron 和 7 wt% (AM-7) 或更多 Ameritop 的复合材料可抑制变形链球菌的生长，而含有高达 10 wt% AIS 的复合材料则不会。在水中储存 1 天和 6 个月后，对照材料和 N-5 复合材料之间的压缩强度或弯曲强度没有观察到显着差异。然而，对于 AM-5 复合材料，两个浸泡周期之间的任一强度参数均存在显着差异。在水中浸泡 1 天或 6 个月后，N-5 和 AM-5 复合材料没有或极少释放银离子。这些结果表明，结合银支撑抗菌材料（例如 Novaron）的光活化树脂复合材料由于其对变形链球菌的抑制作用和良好的机械性能可能在临床上有用。
Dental resin composites with antibacterial activity may be useful for preventing the secondary caries frequently seen around restorations. Three types of silver–supported antibacterial materials (Novaron, Amenitop and AIS) inhibited the growth of the major oral pathogen Streptococcus mutans. Minimum inhibitory amounts in suspensions of Novaron, Amenitop and AIS against S. mutans were 40, 30 and 400 μg/ml, respectively. These antibacterial materials were incorporated into TEGDMA–UDMA–based light–activated resin composite, and the antibacterial activities of these composites were examined. Composites incorporating 5 wt% (N–5) or more of Novaron and 7 wt% (AM–7) or more of Amenitop inhibited the growth of S. mutans, whereas composites incorporating up to 10 wt% of AIS did not. No significant difference in either compressive or flexural strength was observed between the control and N–5 composites after 1 day and 6 months of storage in water. However, for AM–5 composite, there was a significant difference in either strength parameter between the two immersion periods. There was no or extremely little release of silver ions from the N–5 and AM–5 composites after 1 day or 6 months of immersion in water. These results indicated that a light–activated resin composite incorporating silver–supported antibacterial material such as Novaron may be clinically useful due to its inhibitory effect against S. mutans and favorable mechanical properties.
玻璃离子水门汀修复体和继发龋：初步报告。
DOI：
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发表时间：
1996
期刊：
Quintessence international (Berlin, Germany : 1985)
影响因子：
--
作者：
Mjor,IA
通讯作者：
Mjor,IA
影响因子：
2.9
作者：
JEDRYCHOWSKI, JR;CAPUTO, AA;KERPER, S
通讯作者：
KERPER, S