Clinical Characteristics of Ocular Sarcoidosis: A Population-Based Study 1976-2013.

Clinical Characteristics of Ocular Sarcoidosis: A Population-Based Study 1976-2013.
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DOI:
10.1080/09273948.2017.1386791
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发表时间:
2019
影响因子:
3.3
通讯作者:
Smith WM
Smith WM
中科院分区:
医学4区
文献类型:
--
作者:
Ungprasert P;Tooley AA;Crowson CS;Matteson EL;Smith WM

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描述系统性结节病患者眼部受累的流行病学和临床特征。基于全面的个人病历审查,确定了1976-2013年明尼苏达州奥姆斯特德县系统性结节病患者的初始队列。然后审查这些患者的病历,以了解眼部受累情况。共发现345例系统性结节病。23例患者(7%)发生眼部受累。最常见的眼部疾病是葡萄膜炎(61%),其次是干眼病、结膜结节、巩膜外层炎、前巩膜炎和结膜炎。前葡萄膜炎是最常见的葡萄膜炎类型(71%)。葡萄膜炎的视力结局良好,仅1例患者在随访期间丧失3行或更多VA,末次访视时VA低于20/200。7%的结节病患者眼部受累。葡萄膜炎是最常见的眼部疾病。
To characterize the epidemiology and clinical characteristics of ocular involvement in patients with systemic sarcoidosis. An inception cohort of patients with systemic sarcoidosis in 1976–2013 in Olmsted County, Minnesota, was identified based on comprehensive individual medical record review. Medical records of those patients were then reviewed for ocular involvement. A total of 345 incident cases of systemic sarcoidosis were identified. Ocular involvement occurred in 23 patients (7%). The most common ocular disease was uveitis (61%) followed by dry eye disease, conjunctival nodule, episcleritis, anterior scleritis and conjunctivitis. Anterior uveitis was the most common type of uveitis (71%). Visual outcome of uveitis was favorable with only 1 patient lost 3 or more lines of VA during follow-up and had VA of less than 20/200 at last visit. Ocular involvement occurred in 7% of sarcoidosis patients. Uveitis was the most common type of ocular disease.
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