Computer assessment of mild cognitive impairment.
Computer assessment of mild cognitive impairment.
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DOI：
10.3810/pgm.2009.03.1990
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发表时间：
2009-03
影响因子：
4.2
通讯作者：
Zuccolotto A
中科院分区：
文献类型：
--
作者：
Saxton J;Morrow L;Eschman A;Archer G;Luther J;Zuccolotto A
许多老年人随着年龄的增长而出现认知能力下降。认知功能障碍的原因范围从阿尔茨海默病（AD）的破坏性影响到功能障碍的可治疗原因以及许多老年人描述的正常轻度健忘。即使是轻微的认知功能障碍也会影响药物依从性，损害决策能力，并影响驾驶或工作能力。然而，初级保健医生不定期筛查认知困难，许多老年患者没有报告认知问题。在办公室就诊时识别认知障碍将允许早期转诊进行诊断和治疗。轻度认知障碍的计算机评估（CAMCI）是一种自我管理，用户友好的计算机测试，自动评分，可以在安静的空间，如医生的检查室独立完成。本研究的目的是比较CAMCI和简易精神状态检查（MMSE）在524名60岁以上的非痴呆患者中识别轻度认知功能障碍（MCI）的敏感性和特异性，这些患者完成了综合神经心理学和临床评估以及CAMCI和MMSE。我们假设，CAMCI将表现出良好的敏感性和特异性，并将上级MMSE在这些措施。结果表明，MMSE对MCI不敏感。相比之下，CAMCI是高度敏感（86%）和特异性（94%）的MCI在社区居住的非痴呆老年人的人口中的识别。
Many older individuals experience cognitive decline with aging. The causes of cognitive dysfunction range from the devastating effects of Alzheimer’s disease (AD) to treatable causes of dysfunction and the normal mild forgetfulness described by many older individuals. Even mild cognitive dysfunction can impact medication adherence, impair decision making, and affect the ability to drive or work. However, primary care physicians do not routinely screen for cognitive difficulties and many older patients do not report cognitive problems. Identifying cognitive impairment at an office visit would permit earlier referral for diagnostic work-up and treatment. The Computer Assessment of Mild Cognitive Impairment (CAMCI) is a self-administered, user-friendly computer test that scores automatically and can be completed independently in a quiet space, such as a doctor’s examination room. The goal of this study was to compare the sensitivity and specificity of the CAMCI and the Mini Mental State Examination (MMSE) to identify mild cognitive impairment (MCI) in 524 nondemented individuals > 60 years old who completed a comprehensive neuropsychological and clinical assessment together with the CAMCI and MMSE. We hypothesized that the CAMCI would exhibit good sensitivity and specificity and would be superior compared with the MMSE in these measures. The results indicated that the MMSE was relatively insensitive to MCI. In contrast, the CAMCI was highly sensitive (86%) and specific (94%) for the identification of MCI in a population of community-dwelling nondemented elderly individuals.
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影响因子：
2.1
作者：
Billipp, SH
通讯作者：
Billipp, SH
影响因子：
9.9
作者：
Lopez, OL;Becker, JT;DeKosky, ST
通讯作者：
DeKosky, ST
影响因子：
9.9
作者：
Darby, D;Maruff, P;McStephen, M
通讯作者：
McStephen, M
影响因子：
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作者：
Aizenstein, Howard Jay;Nebes, Robert D.;Saxton, Judith A.;Price, Julie C.;Mathis, Chester A.;Tsopelas, Nicholas D.;Ziolko, Scott K.;James, Jeffrey A.;Snitz, Beth E.;Houck, Patricia R.;Bi, Wenzhu;Cohen, Ann D.;Lopresti, Brian J.;DeKosky, Steven T.;Halligan, Edythe M.;Klunk, William E.
通讯作者：
Klunk, William E.
DOI：
10.1111/j.1532-5415.2008.01938.x
发表时间：
2008-11-01
影响因子：
6.3
作者：
Nieto, Maria L.;Albert, Steven M.;Saxton, Judith
通讯作者：
Saxton, Judith