Engineered Fabrication of Enamel-Mimetic Materials

Engineered Fabrication of Enamel-Mimetic Materials
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仿珐琅材料的工程制造

DOI:
10.1016/j.eng.2021.02.027
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发表时间:
2022-05
期刊:
影响因子:
12.8
通讯作者:
Bing Han
Bing Han
中科院分区:
工程技术1区
文献类型:
--
作者:
Lingyun Zhang;Yunfan Zhang;Tingting Yu;Liying Peng;Qiannan Sun;Bing Han

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牙釉质是一种生物组织,主要由排列良好的羟基磷灰石纳米晶和交织的蛋白质基质组成,具有显著的力学和美学行为。然而,要自然再生牙釉质是一项挑战,可能会导致牙髓受累和牙齿脱落。牙釉质作为最坚硬的生物复合材料,长期以来一直被认为是一种很有前途的承载材料。因此,了解釉质形成过程和釉质结构基元的形成机制,对于设计和制造具有高强度和物理弹性的高性能仿生复合材料具有重要意义。人们在模拟牙釉质的微观结构和力学性能方面进行了广泛的研究,并制定了各种釉质类材料的合成方案。结合牙釉质类材料的工程化制备,综述了近年来牙釉质类材料合成策略的研究进展,并对其潜在应用进行了讨论。
Tooth enamel, which is a biological tissue mainly composed of well-aligned hydroxyapatite nanocrystals and an interlaced protein matrix, has remarkable mechanical and aesthetic behaviors. Nevertheless, it is challenging to regenerate enamel naturally, and potential pulp involvement and tooth loss may occur. As the hardest biogenic composite material, enamel has long been regarded as a promising load-bearing material. Thus, understanding the enamel formation process and enamel structural motif mechanisms is important for the design and engineering of high-performance biomimetic composites with high strength and physical resilience. Extensive studies have been conducted on mimicking the microstructure and mechanical properties of tooth enamel, and various enamel-like material synthesis protocols have been developed. In light of the engineering fabrication of enamel-like materials, this review focuses on recent progress in synthetic strategies for enamel-mimetic materials and provides a discussion of the potential applications of these materials.
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