Strength of association between body mass index and physical function scores in paediatric burn patients: A National Institute on Disability, Independent Living, and Rehabilitation Research Burn Model System study.
Strength of association between body mass index and physical function scores in paediatric burn patients: A National Institute on Disability, Independent Living, and Rehabilitation Research Burn Model System study.
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DOI：
10.1016/j.burns.2022.03.001
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发表时间：
2022-06
期刊：
影响因子：
2.7
通讯作者：
Suman, Oscar E.
中科院分区：
文献类型：
--
作者：
Rontoyanni, Victoria G.;Kudlicki, Andrzej;Palackic, Alen;Gibran, Nicole;Stewart, Barclay;Schneider, Jeffrey C.;Ryan, Colleen M.;Murton, Andrew J.;Wolf, Steven E.;Kowalske, Karen;Suman, Oscar E.
体重增加与严重烧伤后早期分解代谢阶段肌肉消耗减少有关。然而，超重和肥胖的非烧伤儿童往往表现出受损的肌肉骨骼功能，这可能会导致身体功能（PF）差。我们的目的是确定严重烧伤儿童出院时的体重指数（BMI）与恢复期间自我报告的PF和护理人员代理报告的PF之间的关联。这是一项在小儿烧伤患者（烧伤时8-17岁）中进行的回顾性多中心纵向研究。PF结局指标为伤后6个月、12个月和24个月时使用PROMIS指标评价的自我报告的活动度、代理人报告的活动度和上肢PF。主要暴露变量为出院时年龄BMI。共分析了118例儿童患者，年龄为11.7 ± 3.3岁，烧伤面积占总体表面积（TBSA）的37.6 ± 18.8%，出院时年龄别BMI为23.1 ± 5.4 kg.m−2。出院时的BMI与烧伤后6个月自我报告的活动性评分无显著相关性（β系数=-0.23，p=0.31），对12个月的活动性有积极影响（β = 0.46，p=0.05），在调整烧伤面积后，对伤后24个月无影响（β =-0.10，p=0.60）。BMI对代理人报告的活动性或上肢PF没有显著影响。出院时BMI越大，烧伤后12个月时自我报告的PF越好，但在6个月或24个月时则不然，这表明体重较大的儿科患者PF恢复得更快。我们的数据表明，较大的体重不会影响烧伤后PF的恢复。
Increased body weight has been associated with reduced muscle wasting in the early catabolic phase after a severe burn. Yet, overweight and obese non-burn children often exhibit impaired musculoskeletal function, which may lead to poor physical function (PF). We aimed to determine the association between body mass index (BMI) at discharge and self-reported PF and caregiver proxy-reported PF during recovery of severely burned children. This is a retrospective multisite longitudinal study in pediatric burn patients (8–17 y old at time of burn). PF outcome measures were self-reported mobility, proxy-reported mobility, and upper extremity PF evaluated using PROMIS measures at 6-, 12-, and 24-months post-injury. Primary exposure variable was BMI-for-age at discharge. A total of 118 pediatric patients, aged 11.7 ± 3.3 y, with burns covering 37.6 ± 18.8 % of their total body surface area (TBSA) and BMI-for-age of 23.1 ± 5.4 kg.m−2 at discharge were analyzed. BMI at discharge was not significantly associated with self-reported mobility scores 6 months after a burn (beta coefficient =−0.23, p=0.31), had a positive effect on mobility at 12 months (beta = 0.46, p=0.05), and no effect at 24 months post-injury (beta=−0.10, p=0.60), when adjusted for burn size. BMI did not have a significant effect on proxy-reported mobility or upper extremity PF. A greater BMI at discharge was associated with improved self-reported PF at 12 months after burn but not at 6 months or 24 months, which suggests a faster recovery of PF in pediatric patients of larger body weight. Our data suggests that a larger body weight does not compromise the recovery of PF after a burn.
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影响因子：
9
作者：
Jeschke MG;Finnerty CC;Emdad F;Rivero HG;Kraft R;Williams FN;Gamelli RL;Gibran NS;Klein MB;Arnoldo BD;Tompkins RG;Herndon DN
通讯作者：
Herndon DN
影响因子：
8
作者：
Barlow, Sarah E.
通讯作者：
Barlow, Sarah E.
影响因子：
6.3
作者：
Malagaris, Ioannis;Herndon, David N.;Sidossis, Labros S.
通讯作者：
Sidossis, Labros S.
影响因子：
2.7
作者：
Alloju, Shashi M.;Herndon, David N.;Suman, Oscar E.
通讯作者：
Suman, Oscar E.
影响因子：
7.2
作者：
Cook, Karon F.;Jensen, Sally E.;Cella, David
通讯作者：
Cella, David