Airway symptoms and lung function in the local population after the oil tank explosion in Gulen, Norway.
Airway symptoms and lung function in the local population after the oil tank explosion in Gulen, Norway.
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DOI：
10.1186/1471-2466-12-76
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发表时间：
2012-12-12
影响因子：
3.1
通讯作者：
Moen BE
中科院分区：
文献类型：
--
作者：
Granslo JT;Bråtveit M;Hollund BE;Irgens Å;Svanes C;Magerøy N;Moen BE
在一个工业港口，装有碳氢化合物混合物（包括含硫化合物）的油罐爆炸起火。这项研究评估了爆炸后1年半附近人群的气道症状和肺功能。一项横断面研究纳入了≥18岁的个体。居住在距离事故现场<6 km的个体（亚组<3 km和3-6 km）构成暴露组，居住在距离事故现场>20 km的个体构成对照组。223名接触者（男性应答率为70%，女性为75%）和179名对照者（男性应答率为51%，女性为65%）完成了问卷调查和肺量测定测试。回归分析包括调整吸烟，职业暴露，特应性，前一个月的感染和年龄。对症状的分析也根据与事故有关的应激反应进行了调整。暴露的个体经历了明显更多的鼻子堵塞（比值比1.7 [95%置信区间1.0，2.8]），溢液（1.6 [1.1，3.3]），鼻刺激（3.4 [2.0，5.9]），咽喉痛（3.1 [1.8，5.5]），早晨咳嗽（3.5 [2.0，5.5]）、每日咳嗽（2.2 [1.4，3.7]）、每年咳嗽>3个月（2.9 [1.5，5.3]）和咳嗽伴痰（1.9 [1.2，3.1]）。鼻部症状和咳嗽有明显增加的趋势，这取决于家庭住址与爆炸地点的接近程度（每日咳嗽，3- 6 km 1.8 [1.0，3.1]，<3 km 3.0 [1.7，6.4]）。暴露组的肺功能测量值显著低于对照组，FEV 1校正的平均差异为−123 mL [95%置信区间为−232，-14]），FEV1%预测值为−2.5 [−5.5，0.5]，FVC为−173 mL [− 297，-50]，FVC%预测值为−3.1 [− 5.9，-0.4]，和气道阻塞（GOLD II/III）。根据横断面分析，生活在油罐爆炸空气污染地区的个人在事件发生后1年半比对照组有更多的气道症状和较低的肺功能。
Oil tanks containing a mixture of hydrocarbons, including sulphuric compounds, exploded and caught fire in an industrial harbour. This study assesses airway symptoms and lung function in the nearby population 1½ years after the explosion. A cross-sectional study included individuals ≥18 years old. Individuals living <6 km (sub-groups <3km and 3–6 km) from the accident site formed the exposed group, individuals living >20 km away formed a control group. A questionnaire and spirometry tests were completed by 223 exposed individuals (response rate men 70%, women 75%) and 179 control individuals (response rate men 51%, women 65%). Regression analyses included adjustment for smoking, occupational exposure, atopy, infection in the preceding month and age. Analyses of symptoms were also adjusted for stress reactions related to the accident. Exposed individuals experienced significantly more blocked nose (odds ratio 1.7 [95% confidence interval 1.0, 2.8]), rhinorrhoea (1.6 [1.1, 3.3]), nose irritation (3.4 [2.0, 5.9]), sore throat (3.1 [1.8, 5.5]), morning cough (3.5 [2.0, 5.5]), daily cough (2.2 [1.4, 3.7]), cough >3 months a year (2.9 [1.5, 5.3]) and cough with phlegm (1.9 [1.2, 3.1]) than control individuals. A significantly increasing trend was found for nose symptoms and cough, depending on the proximity of home address to explosion site (daily cough, 3-6km 1.8 [1.0, 3.1], <3km 3.0 [1.7, 6.4]). Lung function measurements were significantly lower in the exposed group than in the control group, FEV1 adjusted mean difference −123 mL [95% confidence interval −232, -14]), FEV1% predicted −2.5 [−5.5, 0.5], FVC −173 mL [− 297, -50], FVC% predicted −3.1 [− 5.9, -0.4], and airway obstruction (GOLD II/III). Based on cross sectional analyses, individuals living in an area with air pollution from an oil tank explosion had more airway symptoms and lower lung function than a control group 1½ years after the incident.
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影响因子：
10
作者：
Forbes, L. J. L.;Kapetanakis, V.;Anderson, H. R.
通讯作者：
Anderson, H. R.
影响因子：
4.4
作者：
Rash, Carla J.;Coffey, Scott F.;Saladin, Michael E.
通讯作者：
Saladin, Michael E.
DOI：
10.1097/00043764-200207000-00003
发表时间：
2002-07-01
影响因子：
3.2
作者：
Trout, D;Nimgade, A;Earnest, GS
通讯作者：
Earnest, GS
影响因子：
13.6
作者：
Rönmark, E;Lundqvist, A;Nyström, L
通讯作者：
Nyström, L
影响因子：
1.8
作者：
Eid, Jarle;Larsson, Gerry;Carlstedt, Berit
通讯作者：
Carlstedt, Berit