Artificial synaptic modification reveals a dynamical invariant in the pyloric CPG.
Artificial synaptic modification reveals a dynamical invariant in the pyloric CPG.
复制标题
人工突触修饰揭示了幽门 CPG 的动力学不变量。
DOI:
10.1007/s00421-007-0635-0
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发表时间:
2008
影响因子:
3
通讯作者:
Selverston,AllenI
中科院分区:
文献类型:
--
作者:
Reyes,MarceloB;Huerta,Ramón;Rabinovich,MikhailI;Selverston,AllenI
The sequential firing of neurons in central pattern generators (CPGs) is generally thought to be a result of an interaction between intrinsic cellular and synaptic properties of the component neurons. Due to experimental limitations, it is usually difficult to address the role of each of these properties separately. We have done so by using the crustacean stomatogastric CPG and the dynamic clamp technique to measure how the network responds to the selective modification of an individual important synapse. Our results show that the burst periods and the phase lags between the constrictor (LP) and dilator (PD) neurons across preparations showed significant variability during equivalent experimental manipulations. Despite this variability, the ratio between the change in the burst period and the change in the phase lag between the same neurons was tightly preserved in all preparations, revealing a dynamical invariant in the system. This dynamical invariant was preserved despite the individual variability in the period and phase lag measurements, suggesting a tightly regulated constraint between the parameters of the network.
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影响因子:
4.4
作者:
R. Mandell;R. Farrell
通讯作者:
R. Farrell
影响因子:
4.4
作者:
O'Neal,MR;Polse,KA;Sarver,MD
通讯作者:
Sarver,MD
影响因子:
4.4
作者:
O'Neal,MR;Polse,KA
通讯作者:
Polse,KA
DOI:
--
发表时间:
1956
期刊:
影响因子:
--
作者:
G. Bahr
通讯作者:
G. Bahr
影响因子:
--
作者:
MARTOLA, EL;BAUM, JL
通讯作者:
BAUM, JL