Effect of electrical activity of the diaphragm waveform patterns on SpO2 for extremely preterm infants ventilated with neurally adjusted ventilatory assist
Effect of electrical activity of the diaphragm waveform patterns on SpO2 for extremely preterm infants ventilated with neurally adjusted ventilatory assist
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膈肌波形模式电活动对神经调节通气辅助通气的极早产儿 SpO2 的影响
DOI：
10.1002/ppul.25396
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Kawai M
中科院分区：
文献类型：
--
作者：
Araki R;Tomotaki S;Akita M;Motokura K;Tomobe Y;Yamauchi T;Hanaoka S;Tomotaki H;Iwanaga K;Niwa F;Takita J;Kawai M
本研究旨在评估接受神经调节呼吸机辅助(NAVA)的极早产儿的隔膜电活动(EDI)波型与周围血氧饱和度(SpO2)的关系。研究设计我们在一家III级新生儿重症监护病房进行了一项回顾性队列研究。研究对象为2019年11月至2020年11月在本院出生的极早产儿，使用NAVA呼吸机。我们收集了EDI波形数据，并将其分为四种EDI波型，包括相型、中枢性呼吸暂停型、不规则低压型和紧张性爆发型。我们分析了每个患者前15 h可收集数据的EDI波形模式。为了研究EDI波形模式与SpO2之间的关系，我们将每5 分钟一次的数据集作为一个数据单元进行分析。比较减饱和组(Desat[+])和非减饱和组(Desat[-])各波型的比例。结果我们分析了收集的105 h(1260个数据单元)的数据。DESAT(+)组的时相比例明显低于DESAT(-)组(p<； .001)。但DESAT(+)组中枢性呼吸暂停、不规则低电压和紧张性猝发模式的比例明显高于DESAT(-)组(All p<； .05)。结论EDI波形模式的比例对接受NAVA呼吸机治疗的极早产儿SpO2降低有影响。
ObjectiveThis study aimed to evaluate the association between electrical activity of the diaphragm (Edi) waveform patterns and peripheral oxygen saturation (SpO2) in extremely preterm infants who are ventilated with neurally adjusted ventilatory assist (NAVA).Study DesignWe conducted a retrospective cohort study at a level III neonatal intensive care unit. Extremely preterm infants born at our hospital between November 2019 and November 2020 and ventilated with NAVA were included. We collected Edi waveform data and classified them into four Edi waveform patterns, including the phasic pattern, central apnea pattern, irregular low‐voltage pattern, and tonic burst pattern. We analyzed the Edi waveform pattern for the first 15 h of collectable data in each patient. To investigate the association between Edi waveform patterns and SpO2, we analyzed the dataset every 5 min as one data unit. We compared the proportion of each waveform pattern between the desaturation (Desat [+]) and non‐desaturation (Desat [–]) groups.ResultsWe analyzed collected data for 105 h (1260 data units). The proportion of the phasic pattern in the Desat (+) group was significantly lower than that in the Desat (–) group (p< .001). However, the proportions of the central apnea, irregular low‐voltage, and tonic burst patterns in the Desat (+) group were significantly higher than those in the Desat (–) group (allp< .05).ConclusionOur results indicate that proportions of Edi waveform patterns have an effect on desaturation of SpO2in extremely preterm infants who are ventilated with NAVA.
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影响因子：
5.1
作者：
Stein, Howard;Howard, Diane
通讯作者：
Howard, Diane
对已患有或正在发展的支气管肺发育不良的早产儿进行高强度机械通气支持的神经调节通气辅助：单中心经验
影响因子：
4.1
作者：
Y. Jung;Han;Juyoung Lee;S. Shin;E. Kim;J. Choi
通讯作者：
J. Choi
影响因子：
1.4
作者：
Arata Oda;Yoshiya Kamei;T. Hiroma;Tomohiko Nakamura
通讯作者：
Tomohiko Nakamura
影响因子：
38.9
作者：
Clement, Katherine C.;Thurman, Tracy L.;Heulitt, Mark J.
通讯作者：
Heulitt, Mark J.
影响因子：
2.9
作者：
Rosterman, J. L.;Pallotto, E. K.;Manimtim, W. M.
通讯作者：
Manimtim, W. M.