A randomized clinical trial evaluating silicone earplugs for very low birth weight newborns in intensive care.

A randomized clinical trial evaluating silicone earplugs for very low birth weight newborns in intensive care.
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一项随机临床试验评估了重症监护剂出生的新生儿的硅胶耳塞。

DOI:
10.1038/jp.2008.236
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发表时间:
2009-05
影响因子:
2.9
通讯作者:
Lasky, R. E.
Lasky, R. E.
中科院分区:
医学3区
文献类型:
--
作者:
Abou Turk, C.;Williams, A. L.;Lasky, R. E.

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确定佩戴硅胶耳塞的极低出生体重(VLBW)新生儿(<1500 g)是否比对照组长得更大,在发育检查中的表现是否更好。34例VLBW新生儿随机分为是否佩戴耳塞两组。医院结果由研究人员从医疗图表中提取,并对干预状态进行掩盖。14名极低出生体重(ELBW)新生儿(<1000 g)也在18 - 22个月时进行了评估。在调整出生体重后,耳塞组的11名幸存新生儿在月经后34周时比13名对照组重225 g (95% CI: 45, 405)。6名ELBW耳塞婴儿的Bayley心理发展指数比6名对照组高15.53分(95% CI: 3.03, 28.02)。他们的头围大2.59 cm (95% CI: 0.97, 4.21)。耳塞可能促进VLBW新生儿体重增加。至少在ELBW婴儿中,更好的结果可能持续到18 - 22个月。
Determine whether very low birth weight (VLBW) newborns (<1500 g) wearing silicone earplugs grow larger and perform better on developmental exams than controls. VLBW newborns (n=34) were randomized to wearing earplugs or not. Hospital outcomes were abstracted from medical charts by research staff masked to intervention status. Fourteen extremely low birth weight (ELBW) newborns (<1000 g) were also evaluated at 18−22 months. After adjusting for birth weight, 11 surviving newborns in the earplug group were 225 g (95% CI: 45, 405) heavier at 34 weeks post-menstrual age than the 13 controls. Six ELBW earplug infants scored 15.53 points (95% CI: 3.03, 28.02) higher than 6 controls on the Bayley Mental Development Index. Their head circumferences were 2.59 cms (95% CI: 0.97, 4.21) larger. Earplugs may facilitate weight gain in VLBW newborns. Better outcomes may persist at 18−22 months at least in ELBW infants.
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