Characteristics associated with treatment seeking for smoking cessation among heavy-drinking research participants.

Characteristics associated with treatment seeking for smoking cessation among heavy-drinking research participants.
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DOI:
10.3389/fpsyt.2022.951364
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发表时间:
2022
影响因子:
4.7
通讯作者:
Ray, Lara A.
Ray, Lara A.
中科院分区:
医学3区
文献类型:
--
作者:
Green, ReJoyce;Lin, Johnny;Montoya, Amanda K.;Bello, Mariel S.;Grodin, Erica N.;Ryu, Howon;Ho, Diana;Leventhal, Adam M.;Ray, Lara A.

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寻求戒烟治疗具有巨大的临床意义,有可能降低烟草相关的发病率和死亡率。本研究旨在阐明临床变量,区分寻求治疗与非寻求戒烟状态的大量饮酒吸烟者使用数据驱动的方法。该次要数据分析检查了n = 911例(n = 267例女性)每日吸烟和大量饮酒(女性每周饮酒≥ 7次,男性每周饮酒≥ 14次)的受试者,这些受试者入组了使用相同药物治疗的寻求治疗研究(N = 450)或非寻求治疗研究(N = 461)。参与者完成了人口统计学、酒精和香烟使用、酒精渴望、Barratt冲动量表(BIS-11)和威斯康星州吸烟依赖动机清单(WISDM-68)的测量。这些措施被用于随机森林模型,以确定寻求治疗状态的预测因子。在确定寻求治疗状态的最重要的变量是:年龄,每天饮酒的饮料,每天吸烟的香烟,BIS-11认知冲动,WISDM社会环境刺激,WISDM失控,WISDM渴望,和WISDM耐受性。年龄和每天饮酒量是两个最可靠的预测因素,其次是尼古丁渴望和耐受性。那些每天吸烟并且每天饮酒更多的人不太可能属于戒烟治疗寻求组。针对大量饮酒的吸烟者,特别是年轻人,可能有必要让这一群体参与戒烟工作,并减少生命早期尼古丁依赖疾病的负担。
Treatment seeking for smoking cessation has tremendous clinical implications with the potential to reduce tobacco-related morbidity and mortality. The present study seeks to elucidate clinical variables that distinguish treatment seeking versus non-treatment seeking status for smoking cessation in a large sample of heavy drinking smokers using data-driven methods. This secondary data analysis examines n = 911 (n = 267 female) individuals who were daily smokers and heavy drinkers (≥ 7 drinks per week for women, ≥ 14 for men) that were enrolled in either a treatment-seeking study (N = 450) or a non-treatment seeking study (N = 461) using identical pharmacotherapies. Participants completed measures of demographics, alcohol and cigarette use, alcohol craving, the Barratt Impulsiveness Scale (BIS-11), and the Wisconsin Inventory of Smoking Dependence Motives (WISDM-68). These measures were used in a random forest model to identify predictors of treatment seeking status. The top variables of importance in identifying treatment seeking status were: age, drinks per drinking day, cigarettes per smoking day, BIS-11 cognitive impulsivity, WISDM social environmental goads, WISDM loss of control, WISDM craving, and WISDM tolerance. Age and drinks per drinking day were two of the most robust predictors, followed by measures of nicotine craving and tolerance. Individuals who are daily smokers and consume more drinks per drinking day are less likely to belong to the smoking cessationtreatment-seeking group. Targeting heavy drinking smokers, particularly younger individuals, may be necessary to engage this group in smoking cessation efforts and to reduce the burden of disease of nicotine dependence earlier in the lifespan.
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