Defecation function and quality of life in patients with slow-transit constipation after colectomy
Defecation function and quality of life in patients with slow-transit constipation after colectomy
复制标题
结肠切除术后慢传输型便秘患者的排便功能及生活质量
DOI：
10.12998/wjcc.v8.i10.1897
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发表时间：
2020-05
影响因子：
1.1
通讯作者：
Wei-Dong Tong
中科院分区：
文献类型：
--
作者：
Tian Yue;Li Wang;Jing-Wang Ye;Yong Zhang;Hui-Chao Zheng;Hao-De Shen g;Fan Li;Bao-Hua Liu;Wei-Dong Tong
虽然全结肠或次全结肠切除术治疗慢传输型便秘（STC）已被证明是一种确切的治疗方法，但相关的排便功能和生活质量（QOL）的研究很少。目的评价手术治疗STC患者的排便功能及生活质量。方法回顾性分析2013年3月至2017年9月我科收治的30例STC患者的临床资料。记录术前、术中和术后3个月、6个月、1年和2年随访详情。排便功能通过排便、腹痛、腹胀、紧张、泻药、灌肠、腹泻以及Wexner便秘和失禁量表进行评估。采用胃肠道生活质量指数和36项简表调查评价生活质量。结果：大多数患者（93.1%，27/29）在2年随访时表示他们从手术中受益。随访各时间点每周排便次数较术前明显增加（P < 0.05）。同样，与术前值相比，在随访的每个时间点观察到腹胀、紧张、泻药和灌肠剂的使用显著下降（P < 0.05）。术后腹泻得到有效控制，随访2年明显改善。术后6个月、1年、2年的Wexner尿失禁评分明显低于术后3个月的Wexner尿失禁评分（P < 0.05）。与术前相比，术后Wexner便秘评分明显下降（P < 0.05）。因此，可以合理地发现，术后胃肠道QOL指数评分明显增加（P < 0.05），36项简表调查结果显示，术后6个领域（生理作用、情感作用、生理疼痛、活力、心理健康和一般健康）均有显著改善。结论全结肠或次全结肠切除术治疗STC不仅能有效缓解便秘相关症状，而且能提高患者的生活质量。
BACKGROUND Although total or subtotal colectomy for slow-transit constipation (STC) has been proven to be a definite treatment, the associated defecation function and quality of life (QOL) are rarely studied. AIM To evaluate the effectiveness of surgery for STC regarding defecation function and QOL. METHODS From March 2013 to September 2017, 30 patients undergoing surgery for STC in our department were analyzed. Preoperative, intra-operative, and postoperative 3-mo, 6-mo, 1-year, and 2-year follow-up details were recorded. Defecation function was assessed by bowel movements, abdominal pain, bloating, straining, laxative, enema use, diarrhea, and the Wexner constipation and incontinence scales. QOL was evaluated using the gastrointestinal QOL index and the 36-item short form survey. RESULTS The majority of patients (93.1%, 27/29) stated that they benefited from the operation at the 2-year follow-up. At each time point of the follow-up, the number of bowel movements per week significantly increased compared with that of the preoperative conditions (P < 0.05). Similarly, compared with the preoperative values, a marked decline was observed in bloating, straining, laxative, and enema use at each time point of the follow-up (P < 0.05). Postoperative diarrhea could be controlled effectively and notably improved at the 2-year follow-up. The Wexner incontinence scores at 6-mo, 1-year, and 2-year were notably lower than those at the 3-mo follow-up (P < 0.05). Compared with those of the preoperative findings, the Wexner constipation scores significantly decreased following surgery (P < 0.05). Thus, it was reasonable to find that the gastrointestinal QOL index scores clearly increase (P < 0.05) and that the 36-item short form survey results displayed considerable improvements in six spheres (role physical, role emotional, physical pain, vitality, mental health, and general health) following surgery. CONCLUSION Total or subtotal colectomy for STC is not only effective in alleviating constipation-related symptoms but also in enhancing patients’ QOL.
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影响因子：
2.6
作者：
Marchesi, Federico;Sarli, Leopoldo;Roncoroni, Luigi
通讯作者：
Roncoroni, Luigi
影响因子：
2.4
作者：
Wei D;Cai J;Yang Y;Zhao T;Zhang H;Zhang C;Zhang Y;Zhang J;Cai F
通讯作者：
Cai F
影响因子：
1.4
作者：
Frattini, Jared C;Nogueras, Juan J
通讯作者：
Nogueras, Juan J
影响因子：
7.2
作者：
Ware, JE;Gandek, B
通讯作者：
Gandek, B
DOI：
10.3760/cma.j.issn.1671-0274.2007.02.004
发表时间：
2007-03
影响因子：
--
作者：
Jun Jiang;Ning Li;Weiming Zhu;Jie‐shou Li
通讯作者：
Jun Jiang;Ning Li;Weiming Zhu;Jie‐shou Li