Environmental enrichment facilitates amygdala kindling but reduces kindling-induced fear in male rats.
Environmental enrichment facilitates amygdala kindling but reduces kindling-induced fear in male rats.
复制标题
丰富的环境促进了杏仁核的点燃,但减少了雄性大鼠因点燃而产生的恐惧。
作者:
N. Young;Amanda J. Wintink;L. Kalynchuk
The purpose of this experiment was to determine the effect of prior environmental enrichment on the acquisition of kindling and the expression of kindling-induced fear. Sixty male rats were housed either in an enriched environment or in isolation, starting immediately after weaning. As adults, they were subjected to either 50 amygdala-kindling stimulations or sham stimulations, followed by testing in an unfamiliar open field. The kindled-enriched rats acquired the kindled state more quickly than did the kindled-isolated rats, but they also showed less fear in the open field than did the kindled-isolated rats. These results suggest that environmental enrichment has differential effects on kindling acquisition and its behavioral consequences.
影响因子:
56.9
作者:
SUTULA, T;HE, XX;SCOTT, G
通讯作者:
SCOTT, G