Tandem Repeat Diversity in Two Closely Related Hamster Species-The Chinese Hamster (Cricetulus griseus) and Striped Hamster (Cricetulus barabensis).
Tandem Repeat Diversity in Two Closely Related Hamster Species-The Chinese Hamster (Cricetulus griseus) and Striped Hamster (Cricetulus barabensis).
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DOI：
10.3390/biomedicines10040925
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发表时间：
2022-04-18
期刊：
影响因子：
4.7
通讯作者：
中科院分区：
文献类型：
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作者：
中国仓鼠（Cricetulus griseus）和条纹仓鼠（Cricetulus barabensis）是非常接近的物种，具有相似的核型。核型彼此不同的一个罗伯逊重排和X染色体形态。串联重复序列（TR）的进化变异性很高。目前工作的目的是跟踪TR分布在两个非常密切相关的物种的染色体上。条纹仓鼠的基因组尚未测序。我们对中国仓鼠TR进行了分类，然后比较了TR在密切相关物种中的分布模式。由于中国仓鼠TR的相对种属特异性以及两个种属中TR分布的显著差异，中国仓鼠和条纹仓鼠是不同的种属。在同源条纹仓鼠染色体内观察到的TR变异是由自然群体中缺乏近亲繁殖引起的。测试的TR集可用于检查在异染色质区域中观察到的CHO系的不稳定性。
The Chinese hamster (Cricetulus griseus) and striped hamster (Cricetulus barabensis) are very closely related species with similar karyotypes. The karyotypes differ from each other by one Robertsonian rearrangement and X-chromosome morphology. The level of the tandem repeat (TR) sequences’ evolutional variability is high. The aim of the current work was to trace the TR distribution on the chromosomes of two very closely related species. The striped hamster genome has not yet been sequenced. We classified the Chinese hamster TR in the assemblies available and then compared the mode of the TR distribution in closely related species. Chinese and striped hamsters are separate species due to the relative species specificity of Chinese hamster TR and prominent differences in the TR distribution in both species. The TR variation observed within homologous striped hamster chromosomes is caused by a lack of inbreeding in natural populations. The set of TR tested could be used to examine the CHO lines’ instability that has been observed in heterochromatic regions.
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影响因子：
4.4
作者：
Komissarov AS;Gavrilova EV;Demin SJ;Ishov AM;Podgornaya OI
通讯作者：
Podgornaya OI
影响因子：
4.4
作者：
Kaas CS;Kristensen C;Betenbaugh MJ;Andersen MR
通讯作者：
Andersen MR
影响因子：
3.3
作者：
Paço A;Adega F;Meštrović N;Plohl M;Chaves R
通讯作者：
Chaves R
影响因子：
--
作者：
FORD, CE;HAMERTON, JL
通讯作者：
HAMERTON, JL
影响因子：
2.6
作者：
Kuznetsova, Inna S.;Ostromyshenskii, Dmitrii I.;Podgornaya, Olga I.
通讯作者：
Podgornaya, Olga I.