Preterm birth and the timing of puberty: a systematic review.
Preterm birth and the timing of puberty: a systematic review.
复制标题
DOI：
10.1186/s12887-017-0976-8
复制
发表时间：
2018-01-08
期刊：
影响因子：
2.4
通讯作者：
Williams TC
中科院分区：
文献类型：
--
作者：
James E;Wood CL;Nair H;Williams TC
据估计，11%的新生儿是早产，存活率正在提高。早期的研究表明早产和早熟之间存在关联。鉴于与青春期提前相关的不良后果，这可能会对公共卫生产生重大影响。本综述的目的是评估早产后青春期的时间。使用与“早产”、“月经初潮”、“青春期”和“后续研究”相关的术语对Pubmed、Embase、Popline、Global Health和Global Health Library进行了搜索。纳入标准是由青春期或青春期后的青少年和成年人组成的人群；定义参与者早产并将早产结果与足月分娩后的结果进行比较的研究；以及青春期发病的定量评估。偏倚风险评估采用关键评估研究过程的原则进行。我们检索了1051项研究，其中16项符合纳入标准。在女性中，8项研究发现早产和月经初潮时间之间没有关联。五项研究发现早产婴儿发病较早，一项研究发现发病较晚，一项研究显示月经初潮早或晚，这取决于出生体重。研究显示，早产组月经初潮提前的影响范围为- 0.94至- 0.07年，中位数为- 0.3年。在男性中，2项研究显示早产组的青春期早发，5项研究无差异，1项研究显示早产组的青春期晚发。大多数研究没有以标准偏差的平均值的形式呈现结果，排除了荟萃分析。没有足够的数据来处理潜在的混杂因素。已发表的证据并不表明早产会导致青春期的显著加速。这对于公共卫生目的和为早产儿父母提供咨询的临床医生来说应该是令人放心的。本文的在线版本（10.1186/s12887-017-0976-8）包含补充材料，授权用户可使用。
An estimated 11% of births occur preterm, and survival is improving. Early studies suggested an association between preterm birth and earlier puberty. Given the adverse outcomes associated with early puberty this could have significant public health implications. The objective of this review was to assess the timing of puberty after preterm birth. Pubmed, Embase, Popline, Global Health and Global Health Library were searched using terms relating to “premature birth”, “menarche”, “puberty” and “follow up studies”. Inclusion criteria were a population consisting of pubertal or post-pubertal adolescents and adults; studies which defined preterm delivery in participants and compared outcomes to those after term delivery; and a quantitative assessment of pubertal onset. Assessment of risk of bias was conducted using principles from the Critical Appraisal Study Process. Our search identified 1051 studies, of which 16 met the inclusion criteria. In females, 8 studies found no association between preterm birth and the timing of menarche. Five studies found earlier onset in preterm infants, 1 found later onset, and 1 showed both earlier and later menarche, depending on birth weight. The range of effect of studies showing earlier menarche was - 0.94 to −0.07 years in the preterm group, with a median of - 0.3 years. In males, 2 studies showed earlier onset of puberty in the preterm group, 5 showed no difference, and 1 showed later onset. Most studies did not present outcomes in the form of a mean with standard deviation, precluding a meta-analysis. There was insufficient data to address potential confounding factors. The published evidence does not suggest that being born preterm leads to a significant acceleration in the onset of puberty. This should prove reassuring for public health purposes, and for clinicians counseling parents of infants born preterm. The online version of this article (10.1186/s12887-017-0976-8) contains supplementary material, which is available to authorized users.
登录
查看更多内容
DOI：
10.1007/s10552-009-9457-1
发表时间：
2010-02
期刊：
Cancer causes & control : CCC
影响因子：
--
作者：
Epplein M;Novotny R;Daida Y;Vijayadeva V;Onaka AT;Le Marchand L
通讯作者：
Le Marchand L
影响因子：
7.7
作者：
Dalziel, Stuart R.;Parag, Varsha;Harding, Jane E.
通讯作者：
Harding, Jane E.
影响因子：
8
作者：
Atay, Zeynep;Turan, Serap;Bereket, Abdullah
通讯作者：
Bereket, Abdullah
影响因子：
5.4
作者：
Hui, Lai Ling;Leung, Gabriel M.;Schooling, C. Mary
通讯作者：
Schooling, C. Mary
DOI：
10.1097/ede.0b013e31828062b7
发表时间：
2013-03
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
D'Aloisio AA;DeRoo LA;Baird DD;Weinberg CR;Sandler DP
通讯作者：
Sandler DP