A Longitudinal, Genetically Informative, Study of Associations Between Anxiety Sensitivity, Anxiety and Depression
A Longitudinal, Genetically Informative, Study of Associations Between Anxiety Sensitivity, Anxiety and Depression
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焦虑敏感性、焦虑和抑郁之间关联的纵向、遗传信息研究
DOI：
10.1007/s10519-012-9535-0
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发表时间：
2012
影响因子：
2.6
通讯作者：
T. Eley
中科院分区：
文献类型：
--
作者：
H. Zavos;F. Rijsdijk;T. Eley
目前的研究试图检查影响焦虑敏感度、焦虑和抑郁之间的纵向联系的方向。遗传和环境对这些特征的影响在青春期的连续性也被调查了。焦虑敏感、焦虑和抑郁的自我报告是从大约1300对双胞胎和兄弟姐妹中收集的，分两次收集(平均年龄分别为15岁和17岁)。用纵向遗传交叉滞后模型检验了这些性状之间关联的方向和原因。随着时间的推移，所有的性状都是稳定的，这种稳定性解释了时间2的最大比例的变异。然而，也有证据表明变量之间随着时间的推移而相互关联。遗传效应随着时间的推移相当稳定，尽管新的遗传影响在第二个时间点很明显。环境影响往往更具时间特异性。这项研究加深了我们对青春期焦虑敏感、焦虑和抑郁之间的影响方向以及它们之间关联的风险的理解。
The current study sought to examine the direction of influences on longitudinal associations between anxiety sensitivity, anxiety and depression. The continuity of genetic and environmental influences on these traits over adolescence was also investigated. Self reports of anxiety sensitivity, anxiety and depression were collected from approximately 1,300 twin and sibling pairs, on two occasions (mean ages 15 and 17). The direction and etiology of the associations between these traits were examined using longitudinal genetic cross-lagged models. All traits were stable over time and this stability accounted for the largest proportion of variance at time 2. There was, however, also evidence of reciprocal associations between variables over time. Genetic effects were fairly stable across time, although new genetic influences were evident at the second time point. Environmental effects tended to be more time specific. This study adds to our understanding of the direction of effects between anxiety sensitivity, anxiety and depression in adolescence, and the risks underlying their associations.
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遗传对青少年焦虑和抑郁症状相关认知偏差的影响。
影响因子：
6.6
作者：
Zavos HM
通讯作者：
Zavos HM
焦虑敏感性：早期青少年焦虑的前瞻性预测。
影响因子：
10.3
作者：
Schmidt,NormanB;Keough,MeghanE;Mitchell,MelissaA;Reynolds,ElizabethK;Macpherson,Laura;Zvolensky,MichaelJ;Lejuez,CW
通讯作者：
Lejuez,CW
影响因子：
--
作者：
Kovacs,M;Gatsonis,C;Paulauskas,SL;Richards,C
通讯作者：
Richards,C
影响因子：
--
作者：
Moffitt, Terrie E.;Harrington, HonaLee;Poulton, Richie
通讯作者：
Poulton, Richie