Posttransplant cutaneous T-cell lymphoma: case reports and review of the association of calcineurin inhibitor use with posttransplant lymphoproliferative disease risk.
Posttransplant cutaneous T-cell lymphoma: case reports and review of the association of calcineurin inhibitor use with posttransplant lymphoproliferative disease risk.
复制标题
移植后皮肤 T 细胞淋巴瘤：病例报告和钙调神经磷酸酶抑制剂使用与移植后淋巴增殖性疾病风险之间关系的回顾。
作者：
R. Pomerantz;Lauren S Campbell;D. Jukic;L. Geskin
背景
皮肤T细胞淋巴瘤发生在移植后免疫抑制的背景下是罕见的，迄今为止有27例记录。
意见
我们报告2例新的移植后皮肤T细胞淋巴瘤的患者在我们的机构治疗。两人均为男性肾移植受者，平均移植时间为5.3年，正在接受各种多药免疫抑制方案，包括环孢素、他克莫司、吗替麦考酚酯和泼尼松。
结论
这些病例强调了肾移植后皮肤T细胞淋巴瘤与肾移植、环孢素和他克莫司治疗、男性的相关性，并且与B细胞移植后淋巴增生性疾病相比发病较晚。相对于一般人群，皮肤T细胞淋巴瘤的发病率似乎在接受免疫抑制药物的移植受者中增加。
BACKGROUND
Cutaneous T-cell lymphoma occurring in the context of posttransplant immunosuppression is rare, with 27 cases documented to date.
OBSERVATIONS
We report 2 new cases of posttransplant cutaneous T-cell lymphoma in patients treated at our institution. Both were male recipients of renal transplants who had undergone transplantation a mean of 5.3 years previously and were taking various multidrug immunosuppressive regimens, including cyclosporine, tacrolimus, mycophenolate mofetil, and prednisone.
CONCLUSIONS
These cases underscore the association of posttransplant cutaneous T-cell lymphoma with renal transplantation, cyclosporine and tacrolimus therapy, male sex, and later onset compared with B-cell posttransplant lymphoproliferative disease. Relative to the general population, the incidence of cutaneous T-cell lymphoma seems increased among transplant recipients receiving immunosuppressive medications.
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影响因子：
--
作者：
Criscione, Vincent D.;Weinstock, Martin A.
通讯作者：
Weinstock, Martin A.
移植后 T 细胞淋巴母细胞淋巴瘤。
DOI：
10.1016/0002-9343(87)90020-9
发表时间：
1987
期刊：
The American journal of medicine
影响因子：
--
作者：
Lippman,SM;Grogan,TM;Carry,P;Ogden,DA;Miller,TP
通讯作者：
Miller,TP
影响因子：
158.5
作者：
Liebowitz, D
通讯作者：
Liebowitz, D
影响因子：
20.3
作者：
Laliberté, J;Yee, A;Mitchell, BS
通讯作者：
Mitchell, BS