Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates.
Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates.
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DOI：
10.1002/cncr.24760
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发表时间：
2010-02-01
期刊：
影响因子：
6.2
通讯作者：
Ries, Lynn A. G.
中科院分区：
文献类型：
--
作者：
Edwards, Brenda K.;Ward, Elizabeth;Kohler, Betsy A.;Eheman, Christie;Zauber, Ann G.;Anderson, Robert N.;Jemal, Ahmedin;Schymura, Maria J.;Lansdorp-Vogelaar, Iris;Seeff, Laura C.;van Ballegooijen, Marjolein;Goede, S. Luuk;Ries, Lynn A. G.
关键词：
美国癌症协会（ACS），疾病控制和预防中心（CDC），国家癌症研究所（NCI）和北美中央癌症登记协会（NAACCR）每年合作提供有关美国癌症发生和趋势的最新信息。今年的报告包括结直肠癌（CRC）发病率和死亡率的趋势，并强调使用微观模拟建模作为解释过去趋势和预测未来趋势的工具，以协助癌症控制规划和政策决策。有关侵袭性癌症的信息来自NCI、CDC和NAACCR，有关死亡的信息来自CDC的国家卫生统计中心。通过对长期（1975-2006）趋势和短期固定间隔（1997-2006）趋势的联合点分析，估计了所有癌症合并和前15种癌症的年龄标准化发病率和死亡率（2000年美国人口标准）的年度百分比变化。所有统计学检验均为双侧检验。在最近的一段时间内，男性和女性以及大多数种族和民族人群的所有癌症的发病率和死亡率都显着下降（P <0.05）。这些下降主要是由于男性3种最常见癌症的发病率和死亡率下降所致（即，肺癌和前列腺癌以及CRC）以及女性中三种主要癌症中的两种（即，乳腺癌和CRC）。妇女肺癌死亡率的长期趋势显示，在2003年之前，妇女肺癌死亡率的上升幅度越来越小，2003年出现了不显著的下降。微观模拟模型显示，CRC死亡率的下降与筛查的相对较大贡献以及风险因素降低和治疗改善的较小但可证实的影响一致。如果风险因素修正、筛查和治疗保持目前的速度，预计这些下降将继续下去，但随着风险因素的有利趋势以及筛查和最佳治疗的利用率提高，下降可能会进一步加速。虽然癌症发病率和死亡率总体下降令人鼓舞，但某些癌症的发病率和死亡率上升令人关切。
The American Cancer Society (ACS), the Centers for Disease Control and Prevention (CDC), the National Cancer Institute (NCI), and the North American Association of Central Cancer Registries (NAACCR) collaborate annually to provide updated information about cancer occurrence and trends in the United States (U.S.). This year’s report includes trends in colorectal cancer (CRC) incidence and death rates and highlights use of microsimulation modeling as a tool for interpreting past trends and projecting future trends to assist in cancer control planning and policy decisions. Information on invasive cancers was obtained from the NCI, CDC, and NAACCR, and information on deaths from the CDC’s National Center for Health Statistics. Annual percentage changes in the age-standardized incidence and death rates (2000 U.S. population standard) for all cancers combined and for the top 15 cancers were estimated by joinpoint analysis of long-term (1975–2006) trends and short-term fixed interval (1997–2006) trends. All statistical tests were two-sided. Both incidence and death rates from all cancers combined significantly declined (P < .05) in the most recent time period for men and women overall and for most racial and ethnic populations. These decreases were driven largely by declines in both incidence and death rates for the 3 most common cancers in men (i.e., lung and prostate cancers and CRC) and for two of the 3 leading cancers in women (i.e., breast cancer and CRC). The long-term trends for lung cancer mortality in women showed smaller and smaller increases until 2003 when there was a change to a non-significant decline. Microsimulation modeling shows that declines in CRC death rates are consistent with a relatively large contribution from screening and with a smaller but demonstrable impact of risk factor reductions and improved treatments. These declines are projected to continue if risk factor modification, screening, and treatment remain at current rates, but could be further accelerated with favorable trends in risk factors and higher utilization of screening and optimal treatment. Although the decrease in overall cancer incidence and death rates is encouraging, rising incidence and mortality for some cancers are of concern.
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影响因子：
45.3
作者：
Ayanian, JZ;Zaslavsky, AM;Wright, WE
通讯作者：
Wright, WE
影响因子：
8.4
作者：
Butterworth, AS;Higgins, JPT;Pharoah, P
通讯作者：
Pharoah, P
影响因子：
158.5
作者：
Calle, EE;Rodriguez, C;Thun, MJ
通讯作者：
Thun, MJ
DOI：
10.1056/nejmoa0810696
发表时间：
2009-03-26
期刊：
The New England journal of medicine
影响因子：
--
作者：
Andriole GL;Crawford ED;Grubb RL 3rd;Buys SS;Chia D;Church TR;Fouad MN;Gelmann EP;Kvale PA;Reding DJ;Weissfeld JL;Yokochi LA;O'Brien B;Clapp JD;Rathmell JM;Riley TL;Hayes RB;Kramer BS;Izmirlian G;Miller AB;Pinsky PF;Prorok PC;Gohagan JK;Berg CD;PLCO Project Team
通讯作者：
PLCO Project Team
影响因子：
6.2
作者：
Becker, Thomas M.;Espey, David K.;Waxman, Alan G.
通讯作者：
Waxman, Alan G.