SEQADAPT: an adaptable system for the tracking, storage and analysis of high throughput sequencing experiments.
SEQADAPT: an adaptable system for the tracking, storage and analysis of high throughput sequencing experiments.
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DOI：
10.1186/1471-2105-11-377
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发表时间：
2010-07-14
影响因子：
3
通讯作者：
Boyle J
中科院分区：
文献类型：
--
作者：
Burdick DB;Cavnor CC;Handcock J;Killcoyne S;Lin J;Marzolf B;Ramsey SA;Rovira H;Bressler R;Shmulevich I;Boyle J
High throughput sequencing has become an increasingly important tool for biological research. However, the existing software systems for managing and processing these data have not provided the flexible infrastructure that research requires. Existing software solutions provide static and well-established algorithms in a restrictive package. However as high throughput sequencing is a rapidly evolving field, such static approaches lack the ability to readily adopt the latest advances and techniques which are often required by researchers. We have used a loosely coupled, service-oriented infrastructure to develop SeqAdapt. This system streamlines data management and allows for rapid integration of novel algorithms. Our approach also allows computational biologists to focus on developing and applying new methods instead of writing boilerplate infrastructure code. The system is based around the Addama service architecture and is available at our website as a demonstration web application, an installable single download and as a collection of individual customizable services.
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影响因子：
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作者：
Ji, Hongkai;Jiang, Hui;Ma, Wenxiu;Johnson, David S.;Myers, Richard M.;Wong, Wing H.
通讯作者：
Wong, Wing H.
影响因子：
3
作者：
Boyle, John;Rovira, Hector;Shmulevich, Ilya
通讯作者：
Shmulevich, Ilya
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Wold, Barbara
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通讯作者：
Liu, X. Shirley
影响因子：
56.9
作者：
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通讯作者：
Turner, Stephen