Functional Mapping of the Human Somatosensory Cortex with Echo‐Planar MRI

Functional Mapping of the Human Somatosensory Cortex with Echo‐Planar MRI
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利用平面回波 MRI 绘制人类体感皮层的功能图

DOI:
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发表时间:
1995
影响因子:
3.3
通讯作者:
Y. Miyashita
Y. Miyashita
中科院分区:
医学3区
文献类型:
--
作者:
K. Sakai;E. Watanabe;Y. Onodera;H. Itagaki;E. Yamamoto;H. Koizumi;Y. Miyashita

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利用脱氧血红蛋白作为内源性造影剂,利用1.5特斯拉的回声平面成像分析了人类体感皮层的体外源性组织。在三个皮肤区域之一:脚趾、指尖和舌尖上施加频率为3hz的擦洗刺激。副矢状面回波平面切片每2 s采集一次。我们发现,在刺激过程中,病灶带信号强度增加(平均4%),上升时间为2-6秒。这些激活带位于对侧中央后回。三个刺激点的皮层反应在解剖学上是不同的,并且按照脚趾、指尖和舌尖的顺序从内侧到外侧排列。
The somatotopical organization of the human somatosensory cortex was analyzed with echo‐planar imaging at 1.5 Tesla, utilizing deoxyhemoglobin as an endogenous contrast medium. Scrubbing stimulation at a frequency of 3 Hz was applied to one of three cutaneous areas: toes, fingertips, and tongue tip. Parasagittal echo‐planar slices were obtained every 2 s. We found focal bands of increased signal intensity (4% on average) during the stimulation, with a rise time of 2–6 s. These activated bands were located on the contralateral postcentral gyrus. The cortical responses from the three stimulation sites were anatomically distinct and organized medially‐to‐laterally in the order of toes, fingertips, and tongue tip.
DOI: 10.1073/pnas.83.4.1140
发表时间: 1986-02-01
影响因子: 11.1
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通讯作者: RAICHLE, ME
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