Organoid intelligence: Integration of organoid technology and artificial intelligence in the new era of in vitro models

Organoid intelligence: Integration of organoid technology and artificial intelligence in the new era of in vitro models
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类器官智能:类器官技术与人工智能在体外模型新时代的融合

DOI:
10.1016/j.medntd.2023.100276
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发表时间:
2024
影响因子:
--
通讯作者:
Ma, Zhen
Ma, Zhen
中科院分区:
--
文献类型:
--
作者:
Shi, Huaiyu;Kowalczewski, Andrew;Vu, Danny;Liu, Xiyuan;Salekin, Asif;Yang, Huaxiao;Ma, Zhen

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类器官智能通过将尖端的类器官技术与人工智能的力量无缝结合,开创了一个新时代。类器官是由干细胞培养而成的三维微型类器官结构,它为体外模拟复杂的人体器官系统提供了无与伦比的机会。通过类器官技术和人工智能的融合,研究人员获得了加速各学科发现和见解的手段。人工智能算法能够全面分析复杂的类器官行为、复杂的细胞相互作用和对刺激的动态反应。这种协同作用促进了预测模型、精确疾病模拟和个性化医学方法的发展,彻底改变了我们对人类发展、疾病机制和治疗干预的理解。类器官智能有望重塑我们对体外建模的看法,推动我们走向这些先进系统在生物医学研究和药物开发中发挥关键作用的未来。
Organoid Intelligence ushers in a new era by seamlessly integrating cutting-edge organoid technology with the power of artificial intelligence. Organoids, three-dimensional miniature organ-like structures cultivated from stem cells, offer an unparalleled opportunity to simulate complex human organ systems in vitro. Through the convergence of organoid technology and AI, researchers gain the means to accelerate discoveries and insights across various disciplines. Artificial intelligence algorithms enable the comprehensive analysis of intricate organoid behaviors, intricate cellular interactions, and dynamic responses to stimuli. This synergy empowers the development of predictive models, precise disease simulations, and personalized medicine approaches, revolutionizing our understanding of human development, disease mechanisms, and therapeutic interventions. Organoid Intelligence holds the promise of reshaping how we perceive in vitro modeling, propelling us toward a future where these advanced systems play a pivotal role in biomedical research and drug development.
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